Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘gene mutation’

January 10, 2019

Gene therapy: potential and pitfalls

By Susan Buckles susanbuckles

Research is advancing gene therapy as a possible treatment or eventual cure for genetic diseases that bedevil modern science. Gene therapy was conceived over 20 years ago, and until recently, remained largely in the research lab. But gene therapy products are now beginning to be approved by the U.S. Food and Drug Administration for clinical […]

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Tags: Center for Individualized Medicine, David Deyle, gene mutation, gene therapy, Saad Kenderian


August 8, 2018

New pathway in prostate cancer cells suggests possible therapy

By Sara Tiner saratiner

Expanding on previous findings, a group of Mayo researchers continue using discovery research in cells to find options for treating cancers. In their most recent paper, published in Molecular Cell, the team’s research suggest that a drug used for breast cancer may be helpful in some types of prostate cancers. “In the current study we […]

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Tags: basic science, biomedical research, gene mutation, Haojie Huang, Mayo Clinic Cancer Center, prostate cancer


July 12, 2018

Arresting melanoma’s molecular drivers

By Susan Buckles susanbuckles

This post originally appeared on the Center for Individualized Medicine blog on May 15, 2018. Article by Barbara Toman Melanoma, the skin cancer often associated with sun exposure, is on the rise and has no reliable cure. Mayo Clinic is at the forefront of efforts aimed at increasing early detection and treatment of this aggressive disease. The […]

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Tags: Aleksander Sekulic, cancer, Center for Individualized Medicine, gene mutation, immunotherapy, Mayo Clinic Cancer Center, Mayo Clinic Laboratories, melanoma, Minetta Liu


July 5, 2018

Research News Roundup-June 2018

By Elizabeth Zimmermann elizabethzimmermann

Each month, we publish Mayo Clinic’s Research News Roundup. This article includes brief summaries and links to news releases from the preceding month that discuss some of our latest medical research. It also connects readers to related resources. This month’s Roundup includes a number of findings related pancreatic cancer and other gastrointestinal disorders, as well […]

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Tags: basic science, cancer, Center for Individualized Medicine, constipation, diabetes, DNA, DNA testing, gastroenterology, gene mutation, genetic testing, liver cancer, pancreatic cancer


January 9, 2017

Single Allele Mutation Heightens Risk of Early-Onset Parkinson’s

By bobnellis bobnellis

A collaboration of 32 researchers in seven countries, led by scientists at Mayo Clinic’s campus in Florida, found that a mutation in only one allele of a Parkinson’s gene, known as PINK1, increases the risk of early-onset disease. The finding, published recently in the journal Brain, addresses a longstanding debate about whether individuals need to […]

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Tags: gene mutation, neurosciences, Parkinson's disease, Wolfdieter Springer


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