Items Tagged ‘genetics’
January 12, 2021
Physicians have new guidelines for managing rare genetic, metabolic disorders
By Susan Murphy 
Physicians now have a blueprint for diagnosing and managing two specific rare inherited metabolic diseases within a group of nearly 150 congenital disorders of glycosylation. These diseases can cause serious and sometimes fatal malfunctions of several organs at or before birth, as well as chronic debilitating symptoms in adults. The consensus guidelines were published in […]
Tags: Center for Individualized Medicine, clinical research, Eva Morava-Kozicz, genetics, genomics, hereditary diseases, metabolomics, rare disease
January 4, 2021
Research News Roundup – Q4 2020
The year 2020 was a time during which medical and many other researchers around the world focused much of their attention and effort on a single topic – the SARS-CoV-2 virus and related COVID-19 viral infection. However, other research continued, findings were published, and evidence built for improvements in health outcomes and delivery of health […]
Tags: antibiotic, artificial intelligence, brain, cancer research, cardiology, cardiovascular medicine, Center for Individualized Medicine, Center for the Science of Health Care Delivery, clinical research, clinical trials, collaboration, coronary artery disease
December 9, 2020
Diversifying genomic medicine beyond genes
The work to improve health and health care is ongoing and ever-evolving. It takes many shapes, from streamlining delivery to improving care and pursuing inclusive medical research to help develop precision medicine for all populations. This was a key element of the Arizona Return of Actionable Variants Empirical, or RAVE, study, which brought genomic medicine to […]
Tags: biomedical ethics, Center for Individualized Medicine, clinical trials, diversity, DNA, genetics, genomics, health disparities, Iftikhar Kullo, Richard Sharp
September 16, 2020
Mayo Clinic research advances diagnostics to lead COVID-19 pandemic response
By Susan Murphy
When COVID-19 spread across the U.S. in early March, Mayo Clinic’s Advanced Diagnostic Laboratory (ADL) urgently responded. Lab spaces were transitioned, staff reassigned and funding approvals were fast-tracked. Its goals were to accelerate research, development, translation and implementation of novel tests in order to discover life-saving treatments and diagnostics. “ADL houses a lab structure for […]
Tags: Ann Moyer, antibodies, Benjamin Kipp, Bobbie Pritt, Center for Individualized Medicine, COVID-19, Department of Laboratory Medicine and Pathology, Dietrich Matern, Elitza Theel, genetics, genomics, John Mills
September 4, 2020
Mayo Clinic Research in the news — 9/4/2020
A wide range of topics were covered by news media over the last week, citing Mayo Clinic Research or including Mayo researchers’ perspectives. Below are excerpts from some of these articles, as well as links to the full stories online. Read on for news about gluten-free cosmetics, daylight savings time, advances in understanding in Alzheimer’s […]
Tags: ALS, Alzheimer's disease, amnesia, amyotrophic lateral sclerosis, Andrea Boon, Andrea Tooley, artificial intelligence, Barry Borlaug, cancer, cardiology, Carrie Thompson, clinical research
September 3, 2020
By Advancing the Science contributor
Heart patients who undergo percutaneous coronary intervention (PCI) or stent placement― nonsurgical procedures to improve blood flow to the heart ― are typically prescribed anti-platelet therapy to avoid blood clots that can lead to a heart attack or stroke. New research from the international TAILOR-PCI trial, the largest pharmacogenetics clinical trial in cardiology, suggests that genetic testing could […]
Tags: antiplatelet, cardiology, Center for Individualized Medicine, Charanjit Rihal, clinical trials, coronary artery disease, gene varient, genetics, heart disease, Kent Bailey, Michael Farkouh, Naveen Pereira
August 21, 2020
Mayo Clinic Research in the news — 8/21/2020
A wide range of Mayo Clinic expertise was highlighted in the past week, with local, national and international media outlets quoting researchers and referring to Mayo Clinic research findings. Following are a selection of these news articles, with a brief excerpt and link to the full story on the appropriate websites. For ease of review, […]
Tags: Alzheimer's disease, Andrew Badley, blood pressure, Bobbi Pritt, Brian Mohney, cardiology, Centers for Disease Control and Prevention, COVID-19, diabetes, emergency department, epidemiology, genetics
August 20, 2020
Could population genetic screening improve public health?
Hereditary BRCA-related breast and ovarian cancer, Lynch syndrome and familial hypercholesterolemia are estimated to be relatively prevalent in the general population but poorly found using traditional risk screening. In a typical medical practice, genetic testing for these conditions is based on personal or family history, ethnic background or other demographic characteristics, that may not always […]
Tags: breast cancer, cancer genomics, Center for Individualized Medicine, genetic testing, genetics, hereditary cancer, hereditary diseases, Lynch syndrome, Matthew Ferber, ovarian cancer, population health
March 24, 2020
By Susan Murphy
By Sharon Rosen Patients suffering from depression, anxiety and substance use disorders often search for years to find treatment. Studies have shown that during this time gap, patients’ symptoms worsen, increasing their risk for other chronic illnesses, shortened lifespan and poor quality of life. Mayo Clinic statistical geneticist Joanna Biernacka, Ph.D. and her colleagues are working to […]
Tags: anxiety, biobank, Center for Individualized Medicine, depression, genetic testing, genetics, Joanna Biernacka, Mark Frye, psychiatry, substance abuse disorder
March 10, 2020
Patient’s premature aging symptoms tied to shorter DNA strands
At only 27-years-old, Morgan Cook recalls the days when she had an abundant amount of energy. “I would lift weights. I would do cardio. I would – you name it, I would do it. I was a lot more active,” says Cook. “I felt like I was able to do more things with friends. I […]
Tags: Center for Individualized Medicine, DNA, genetic counseling, genetic testing, genetics, Mrinal Patnaik, rare disease, short telomere syndrome