Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘genetics’

March 24, 2020

Individualized care for psychiatric disorders — Mayo Clinic Biobank + genetic testing could pave the way

By Susan Murphy Susan Murphy

By Sharon Rosen Patients suffering from depression, anxiety and substance use disorders often search for years to find treatment. Studies have shown that during this time gap, patients’ symptoms worsen, increasing their risk for other chronic illnesses, shortened lifespan and poor quality of life. Mayo Clinic statistical geneticist Joanna Biernacka, Ph.D. and her colleagues are working to […]

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Tags: anxiety, biobank, Center for Individualized Medicine, depression, genetic testing, genetics, Joanna Biernacka, Mark Frye, psychiatry, substance abuse disorder


March 10, 2020

Patient’s premature aging symptoms tied to shorter DNA strands

By Colette Gallagher Colette Gallagher

At only 27-years-old, Morgan Cook recalls the days when she had an abundant amount of energy. “I would lift weights. I would do cardio. I would – you name it, I would do it. I was a lot more active,” says Cook. “I felt like I was able to do more things with friends. I […]

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Tags: Center for Individualized Medicine, DNA, genetic counseling, genetic testing, genetics, Mrinal Patnaik, rare disease, short telomere syndrome


November 21, 2019

Getting to the heart of cancer treatment side effects

By Advancing the Science contributor Advancing the Science contributor

By Sara Nick Cancer care has come a long way in recent decades, with some types achieving survival rates of 90% or more. But longer survival times have introduced new consequences: namely, common cancer treatments can lead to an increased risk of serious heart problems later on. “Chemotherapy and radiation are lifesaving, but we’re playing […]

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Tags: basic science, biobank, cardiology, Carolyn Landolfo, collaboration, DeLisa Fairweather, discovery research, genetic testing, genetics, Jordan Ray, Mayo Clinic Cancer Center, Nadine Norton


October 14, 2019

BEAUTY Update: Progress in breast cancer research

By Advancing the Science contributor Advancing the Science contributor

By Barbara J. Toman Chemotherapy is a standard breast cancer treatment, used for aggressive biology breast cancer to shrink tumors in the breast and lymph nodes before surgery, assess response and destroy any undetected cancer cells elsewhere in the patient. But some breast tumors don’t respond well to chemotherapy, putting patients at high risk of […]

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Tags: breast cancer, cancer, Center for Individualized Medicine, chemotherapy, clinical trials, genetics, genomics, individualized medicine, Judy Boughey, Liewei Wang, Matthew Goetz, Mayo Clinic Cancer Center


June 5, 2019

Mayo Clinic at ASCO 2019

By Elizabeth Zimmermann Elizabeth Zimmermann

Every year the American Society of Clinical Oncology (ASCO) hosts a gathering of cancer researchers and clinicians from around the world to teach and learn from each other, sharing their research and innovations in patient care. ASCO’s mission is “conquering cancer through research education, and promotion of the highest quality patient care” – a theme […]

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Tags: cancer, cancer prevention, CAR-T, clinical trials, colorectal cancer, DNA, genetics, Hao Xie, hematology, Katharine Price, Mayo Clinic Cancer Center, multiple myeloma


May 29, 2019

Sudden Cardiac Death: Defining the Risk for Surviving Relatives

By Susan Buckles Susan Buckles

Article by Barbara Toman A young person’s sudden death from cardiac arrest is doubly devastating. Just when family members are mourning the unexpected loss, they might also be wondering if tArhe cause was inherited heart disease — and if they too are at risk. Often there’s no easy answer. Unlike certain cancers with strong links […]

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Tags: cardiovascular disease, Center for Individualized Medicine, genetics, heart disease, Joseph Maleszewski, sudden cardiac arrest


March 28, 2019

When the shoelaces fray: short telomere syndromes

By Advancing the Science contributor Advancing the Science contributor

Article by Barbara Toman Unlike gray hair, one of the most significant signs of aging is invisible to the naked eye. Deep inside cells, at the tips of thread-like chromosomes, structures known as telomeres protect chromosomes from deterioration—a bit like the way caps at the ends of shoelaces prevent fraying. Telomeres naturally shorten as people […]

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Tags: Center for Individualized Medicine, DNA, genetics, Mrinal Patnaik, short telomere syndrome


January 17, 2019

RIGHT 10K: Blazing a trail to health care’s future

By Susan Buckles Susan Buckles

Article by Barbara Toman This article originally appeared on the Center for Individualized Medicine blog Mayo Clinic’s Center for Individualized Medicine (CIM) is nearing the finish line of the first stage of its unique RIGHT 10K study—an effort that doesn’t involve running shoes but nevertheless is paving the way to prescribing medications matched to a […]

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Tags: Center for Individualized Medicine, Eric Matey, genetics, Jessica Wright, pharmacogenomics, RIGHT 10K study


November 15, 2018

Meet Lisa Schimmenti: Searching for drug therapies to treat hearing loss

By Susan Buckles Susan Buckles

This article originally appeared on the Center for Individualized Medicine blog on Oct. 4, 2018 Article by Sharon Rosen   Lisa Schimmenti, M.D. has always been fascinated with Helen Keller and all she accomplished, in spite of being blind and deaf from a very young age. As the newly appointed chair of Mayo Clinic’s Department of […]

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Tags: basic science, Center for Individualized Medicine, genetics, Lisa Schimmenti, zebrafish


October 10, 2018

Mayo lab scientists collaborate to paint a better picture of patient health

By Caitlin Doran Caitlin Doran

On September 24, 2018, the National Institutes of Health  (NIH) awarded Mayo Clinic funding to serve as the new Metabolomics Research Core for the Undiagnosed Diseases Network. In this article, we explore the role of metabolomics in medicine at Mayo Clinic, both in research and in patient care. And we celebrate the role that Mayo Clinic […]

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Tags: Devin Oglesbee, genetics, genomics, Ian Lanza, Mayo Clinic Laboratories, metabolomics


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