Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘genomics’

November 14, 2019

Late relapse for breast cancer patients: Scientists work to predict risk

By Advancing the Science contributor Advancing the Science contributor

By Sara Nick Many breast cancer patients develop recurrence years after the original diagnosis, despite following a long-term medication protocol after initial treatment. Mayo Clinic scientists are taking a closer look at which factors contribute to risk of recurrence, including the subtype of cancer patients have. “Understanding which patients are still at risk of late […]

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Tags: breast cancer, E. Aubrey Thompson, genomics, Mayo Clinic Cancer Center, Saranya Chumsri


November 6, 2019

Precision genomics may offer clues to unexplained low blood cell counts

By Advancing the Science contributor Advancing the Science contributor

By Jay Furst Precision genomics has opened the door to identifying the drivers for cancer and other diseases. Its value as a diagnostic tool isn’t limited to the underlying disease biology, however. It also can help diagnose and determine targeted therapies for patients with unexplained illnesses. Mrinal Patnaik, M.B.B.S., a Mayo Clinic hematologist, and colleagues […]

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Tags: blood cancer, Center for Individualized Medicine, genomics, hematology, Mayo Clinic Proceedings, Mrinal Patnaik, precision medicine


October 14, 2019

BEAUTY Update: Progress in breast cancer research

By Advancing the Science contributor Advancing the Science contributor

By Barbara J. Toman Chemotherapy is a standard breast cancer treatment, used for aggressive biology breast cancer to shrink tumors in the breast and lymph nodes before surgery, assess response and destroy any undetected cancer cells elsewhere in the patient. But some breast tumors don’t respond well to chemotherapy, putting patients at high risk of […]

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Tags: breast cancer, cancer, Center for Individualized Medicine, chemotherapy, clinical trials, genetics, genomics, individualized medicine, Judy Boughey, Liewei Wang, Matthew Goetz, Mayo Clinic Cancer Center


September 18, 2019

Genomics and computer science intersect to improve patient care

By Advancing the Science contributor Advancing the Science contributor

By Sharon Rosen Computational genomics is a field that brings high-performance computing resources to drive precision medicine research toward new discoveries. However, when over 50 Mayo Clinic physicians, researchers and students gathered in June to participate in the Computational Genomics Course, the emphasis was on the needs of the patient. The annual week-long intensive course […]

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Tags: Center for Individualized Medicine, education, epigenetics, genomics, Justin Nguyen, Nidhi Jalan Sakrikar, research education, Timothy Curry, University of Illinois Urbana-Champaign


September 11, 2019

Targeting therapy to each patient’s unique cancer

By Advancing the Science contributor Advancing the Science contributor

Article by Sara Damore As DNA sequencing technology helps bring genetic factors driving disease into focus, researchers have developed new cancer therapies to target a patient’s unique cancer, especially for those who do not respond to standard therapy. Funda Meric-Bernstam, M.D., a physician-scientist at MD Anderson Cancer Center, will speak on Decision Support  for Precision […]

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Tags: Alan Bryce, cancer, Center for Individualized Medicine, clinical trials, DNA, genomics, hematology, Mayo Clinic Cancer Center, oncology, personalized medicine


July 24, 2019

Taking the guesswork out of finding the right depression therapy: Meet William Bobo, M.D.

By Advancing the Science contributor Advancing the Science contributor

By Sharon Rosen Depression can touch every aspect of a person’s life – affecting the way they think, feel and behave. It is also the leading medical condition for those who complete suicide. Getting the right therapy is crucial. But for patients suffering from the disorder, finding an effective treatment often involves trial and error. […]

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Tags: Arjun Athreya, artificial intelligence, Center for Individualized Medicine, genomics, Leiwei Wang, mental health, psychiatry, Richard Weinshilboum, University of Illinois Urbana-Champaign, William Bobo


February 12, 2019

Mayo Clinic discovery advances potential individualized treatment for mesothelioma

By Susan Buckles Susan Buckles

Large chromosomal rearrangements present in mesothelioma could make it possible to understand which patients are likely respond to immunotherapy,  researchers at the Mayo Clinic Center for Individualized Medicine  have discovered. The research is published in the Journal of Thoracic Oncology. “What we’ve shown so far is that these large complex chromosomal rearrangements are frequent in […]

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Tags: Aaron Mansfield, basic science, cancer, Center for Individualized Medicine, DNA, genomics, George Vasmatzis, immunology, Mayo Clinic Cancer Center, mesothelioma


October 10, 2018

Mayo lab scientists collaborate to paint a better picture of patient health

By Caitlin Doran Caitlin Doran

On September 24, 2018, the National Institutes of Health  (NIH) awarded Mayo Clinic funding to serve as the new Metabolomics Research Core for the Undiagnosed Diseases Network. In this article, we explore the role of metabolomics in medicine at Mayo Clinic, both in research and in patient care. And we celebrate the role that Mayo Clinic […]

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Tags: Devin Oglesbee, genetics, genomics, Ian Lanza, Mayo Clinic Laboratories, metabolomics


August 14, 2018

Research suggests genetics are key in treating night sweats

By Advancing the Science contributor Advancing the Science contributor

This post originally was published on the Center for Individualized Medicine blog on June 25, 2018 Article by Heather Carlson Women going through menopause know all too well the discomfort associated with night sweats. Hormone therapy is often used to prevent night sweats. But finding the right dose of estrogen can be tricky, with some […]

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Tags: Ann Moyer, Center for Individualized Medicine, genomics, menopause, pharmacogenomics, Richard Weinshilboum, Virginia Miller, women's health


August 2, 2018

Research News Roundup-July 2018

By Elizabeth Zimmermann Elizabeth Zimmermann

The Mayo Clinic Research News Roundup includes brief summaries and links to research-related news releases from the past month. It also connects readers to associated resources. Read on for more information from Mayo Clinic Research. Anesthesia, surgery linked to subtle decline in memory and thinking in older adults, Mayo study finds In adults over 70, exposure to general […]

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Tags: aging, Alzheimer's disease, basic science, DNA, genomics, Mayo Clinic Proceedings, Mayo Clinic Study of Aging, neurology, ovarian cancer, precision medicine, Research News Roundup


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