Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘genomics’

February 12, 2019

Mayo Clinic discovery advances potential individualized treatment for mesothelioma

By Susan Buckles susanbuckles

Large chromosomal rearrangements present in mesothelioma could make it possible to understand which patients are likely respond to immunotherapy,  researchers at the Mayo Clinic Center for Individualized Medicine  have discovered. The research is published in the Journal of Thoracic Oncology. “What we’ve shown so far is that these large complex chromosomal rearrangements are frequent in […]

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Tags: Aaron Mansfield, basic science, cancer, Center for Individualized Medicine, DNA, genomics, George Vasmatzis, immunology, Mayo Clinic Cancer Center, mesothelioma


October 10, 2018

Mayo lab scientists collaborate to paint a better picture of patient health

By Caitlin Doran caityrosey

On September 24, 2018, the National Institutes of Health  (NIH) awarded Mayo Clinic funding to serve as the new Metabolomics Research Core for the Undiagnosed Diseases Network. In this article, we explore the role of metabolomics in medicine at Mayo Clinic, both in research and in patient care. And we celebrate the role that Mayo Clinic […]

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Tags: Devin Oglesbee, genetics, genomics, Ian Lanza, Mayo Clinic Laboratories, metabolomics


August 14, 2018

Research suggests genetics are key in treating night sweats

By Advancing the Science contributor advancingthescience

This post originally was published on the Center for Individualized Medicine blog on June 25, 2018 Article by Heather Carlson Women going through menopause know all too well the discomfort associated with night sweats. Hormone therapy is often used to prevent night sweats. But finding the right dose of estrogen can be tricky, with some […]

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Tags: Ann Moyer, Center for Individualized Medicine, genomics, menopause, pharmacogenomics, Richard Weinshilboum, Virginia Miller, women's health


August 2, 2018

Research News Roundup-July 2018

By Elizabeth Zimmermann elizabethzimmermann

The Mayo Clinic Research News Roundup includes brief summaries and links to research-related news releases from the past month. It also connects readers to associated resources. Read on for more information from Mayo Clinic Research. Anesthesia, surgery linked to subtle decline in memory and thinking in older adults, Mayo study finds In adults over 70, exposure to general […]

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Tags: aging, Alzheimer's disease, basic science, DNA, genomics, Mayo Clinic Proceedings, Mayo Clinic Study of Aging, neurology, ovarian cancer, precision medicine, Research News Roundup


August 1, 2018

Mentorship program makes research aspirations a reality

By Caitlin Doran caityrosey

Mrinal Patnaik, M.B.B.S., is a physician in the Department of Hematology at Mayo Clinic with a keen interest in the clinical management of blood cancers. In recent years, however, Dr. Patnaik realized he wanted to develop a deeper understanding of the disease biology of these cancers and the ways that precision genomics could be used […]

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Tags: Center for Clinical and Translational Science, Center for Individualized Medicine, education, epigenetics, genomics, hematology, Mrinal Patnaik, research education


April 23, 2018

Registration opens for Individualizing Medicine 2018 Conference

By Susan Buckles susanbuckles

This post originally appeared on the Individualized Medicine blog on April 3, 2018. By Sharon Rosen Gene editing, artificial intelligence, pharmacogenomics and a new era of genomic testing to identify and hopefully treat inherited cancer are just a few of the emerging areas of precision medicine that have the potential to transform patient care. These […]

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Tags: Center for Individualized Medicine, genomics, individualized medicine, Individualizing Medicine Conference, microbiome, pharmacogenomics, precision medicine, Timothy Curry


February 22, 2018

Three strikes, then a home run: Paige’s path to a diagnosis

By Susan Buckles susanbuckles

Paige Whorton’s zeal for life is infectious. “I like parasailing, exploring, and zip lining — daredevil stuff,” she says with a giggle. However, pain in her joints, building for years, was slowing her down. “My bones and joints would hurt when I would run. I couldn’t do anything fun with friends. It was more like, […]

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Tags: Brendan Lanpher, Center for Individualized Medicine, Erin Conboy, Filippo Pinto e Vairo, genetic testing, genomics


January 30, 2018

How does a genomic tumor board impact patient care?

By Colette Gallagher colettegallagher

The outcomes from a Mayo Clinic study published in Oncotarget found value in having an established genomic tumor board, and using genomics for certain patients. The experience of the Genomic Tumor Board has promoted an evolution in the practice according to Alan Bryce, M.D., a Mayo Clinic oncologist, and co-first author on the study. “There is an emerging […]

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Tags: Alan Bryce, cancer, Center for Individualized Medicine, genetic testing, genomics, Jan Egan, Mayo Clinic Cancer Center, tumor


January 25, 2018

Happy New Year!

By Elizabeth Zimmermann elizabethzimmermann

It’s been a few weeks since 2018 started, and you may have thought you were done celebrating. If you’ve had your fill of holiday food and frivolity, maybe you’re looking for something else to tickle your fancy. If so, perhaps some of the new happenings from Mayo Clinic research and research education may be just the thing. Help us […]

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Tags: basic science, genomics, Iftikhar Kullo, imaging, immunology, Richard Ehman


December 12, 2017

What in the world is an extracellular vesicle? Find out this and more from Mayo Clinic Research

By Elizabeth Zimmermann elizabethzimmermann

Not an extraterrestrial spaceship, but something equally fascinating—extracellular vesicles are biological nanoparticles secreted by all cells. Extracellular vesicles contain biomolecules, such as RNA, proteins, lipids and carbohydrates, which play an important role in cell communication. Extracellular vesicles are just part of what you can learn about on the newest Mayo Clinic research websites. And as you read, we […]

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Tags: genetics, genomics, heart disease, Joy Wolfram, nanomedicine


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