Items Tagged ‘genomics’
February 18, 2020
By Susan Murphy 
A collaborative team of Mayo Clinic scientists is studying an innovative strategy for treating advanced cancer, using genomics and human tumor samples as their guide. The novel approach, called Ex Vivo, creates a miniature cancer replica for testing therapies outside a patient’s body, combined with a comprehensive genomic analysis of a patient’s cancer cells. “We […]
Tags: biomarkers, cancer, cancer genomics, Center for Individualized Medicine, genomics, George Vasmatzis, individualized medicine, Mayo Clinic Cancer Center, Minetta Liu, Panos Anastasiadis, personalized medicine
January 9, 2020
In a first, researchers sequence single bacterial cells, paving path for rapid sepsis test
By Susan Murphy
For the first time, Mayo Clinic researchers are sequencing the genomic contents of single bacterial cells. The technique may pave the way for a potential lifesaving test for sepsis, a serious and sometimes deadly condition caused by the body’s response to an infection. Rather than waiting for days to identify the source of a patient’s […]
Tags: antibacterial resistance, basic science, biomedical engineering, Center for Individualized Medicine, deep space medicine, genomics, Heidi Nelson, infectious disease, Marina Walther-Antonio, Nicholas Chia, Robin Patel, sepsis
November 14, 2019
Late relapse for breast cancer patients: Scientists work to predict risk
By Advancing the Science contributor
By Sara Nick Many breast cancer patients develop recurrence years after the original diagnosis, despite following a long-term medication protocol after initial treatment. Mayo Clinic scientists are taking a closer look at which factors contribute to risk of recurrence, including the subtype of cancer patients have. “Understanding which patients are still at risk of late […]
Tags: breast cancer, E. Aubrey Thompson, genomics, Mayo Clinic Cancer Center, Saranya Chumsri
November 6, 2019
Precision genomics may offer clues to unexplained low blood cell counts
By Advancing the Science contributor
By Jay Furst Precision genomics has opened the door to identifying the drivers for cancer and other diseases. Its value as a diagnostic tool isn’t limited to the underlying disease biology, however. It also can help diagnose and determine targeted therapies for patients with unexplained illnesses. Mrinal Patnaik, M.B.B.S., a Mayo Clinic hematologist, and colleagues […]
Tags: blood cancer, Center for Individualized Medicine, genomics, hematology, Mayo Clinic Proceedings, Mrinal Patnaik, precision medicine
October 14, 2019
BEAUTY Update: Progress in breast cancer research
By Advancing the Science contributor
By Barbara J. Toman Chemotherapy is a standard breast cancer treatment, used for aggressive biology breast cancer to shrink tumors in the breast and lymph nodes before surgery, assess response and destroy any undetected cancer cells elsewhere in the patient. But some breast tumors don’t respond well to chemotherapy, putting patients at high risk of […]
Tags: breast cancer, cancer, Center for Individualized Medicine, chemotherapy, clinical trials, genetics, genomics, individualized medicine, Judy Boughey, Liewei Wang, Matthew Goetz, Mayo Clinic Cancer Center
September 18, 2019
Genomics and computer science intersect to improve patient care
By Advancing the Science contributor
By Sharon Rosen Computational genomics is a field that brings high-performance computing resources to drive precision medicine research toward new discoveries. However, when over 50 Mayo Clinic physicians, researchers and students gathered in June to participate in the Computational Genomics Course, the emphasis was on the needs of the patient. The annual week-long intensive course […]
Tags: Center for Individualized Medicine, education, epigenetics, genomics, Justin Nguyen, Nidhi Jalan Sakrikar, research education, Timothy Curry, University of Illinois Urbana-Champaign
September 11, 2019
Targeting therapy to each patient’s unique cancer
By Advancing the Science contributor
Article by Sara Damore As DNA sequencing technology helps bring genetic factors driving disease into focus, researchers have developed new cancer therapies to target a patient’s unique cancer, especially for those who do not respond to standard therapy. Funda Meric-Bernstam, M.D., a physician-scientist at MD Anderson Cancer Center, will speak on Decision Support for Precision […]
Tags: Alan Bryce, cancer, Center for Individualized Medicine, clinical trials, DNA, genomics, hematology, Mayo Clinic Cancer Center, oncology, personalized medicine
July 24, 2019
Taking the guesswork out of finding the right depression therapy: Meet William Bobo, M.D.
By Advancing the Science contributor
By Sharon Rosen Depression can touch every aspect of a person’s life – affecting the way they think, feel and behave. It is also the leading medical condition for those who complete suicide. Getting the right therapy is crucial. But for patients suffering from the disorder, finding an effective treatment often involves trial and error. […]
Tags: Arjun Athreya, artificial intelligence, Center for Individualized Medicine, genomics, Liewei Wang, mental health, psychiatry, Richard Weinshilboum, University of Illinois Urbana-Champaign, William Bobo
February 12, 2019
Mayo Clinic discovery advances potential individualized treatment for mesothelioma
Large chromosomal rearrangements present in mesothelioma could make it possible to understand which patients are likely respond to immunotherapy, researchers at the Mayo Clinic Center for Individualized Medicine have discovered. The research is published in the Journal of Thoracic Oncology. “What we’ve shown so far is that these large complex chromosomal rearrangements are frequent in […]
Tags: Aaron Mansfield, basic science, cancer, Center for Individualized Medicine, DNA, genomics, George Vasmatzis, immunology, Mayo Clinic Cancer Center, mesothelioma
October 10, 2018
Mayo lab scientists collaborate to paint a better picture of patient health
On September 24, 2018, the National Institutes of Health (NIH) awarded Mayo Clinic funding to serve as the new Metabolomics Research Core for the Undiagnosed Diseases Network. In this article, we explore the role of metabolomics in medicine at Mayo Clinic, both in research and in patient care. And we celebrate the role that Mayo Clinic […]
Tags: Devin Oglesbee, genetics, genomics, Ian Lanza, Mayo Clinic Laboratories, metabolomics