Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘genomics’

October 6, 2020

Mayo scientists develop mathematical index to distinguish healthy microbiome from diseased

By Susan Murphy Susan Murphy

What causes some people to develop chronic diseases such as rheumatoid arthritis, cancer and metabolic syndrome while others stay healthy? A major clue could be found in their gut microbiome — the trillions of microbes living inside the digestive system that regulate various bodily functions. To utilize the huge population of tiny organisms as a […]

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Tags: Center for Individualized Medicine, genomics, gut health, Jaeyun Sung, microbiome, multiple chronic conditions


September 16, 2020

Mayo Clinic research advances diagnostics to lead COVID-19 pandemic response

By Susan Murphy Susan Murphy

When COVID-19 spread across the U.S. in early March, Mayo Clinic’s Advanced Diagnostic Laboratory (ADL) urgently responded. Lab spaces were transitioned, staff reassigned and funding approvals were fast-tracked. Its goals were to accelerate research, development, translation and implementation of novel tests in order to discover life-saving treatments and diagnostics. “ADL houses a lab structure for […]

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Tags: Ann Moyer, antibodies, Benjamin Kipp, Bobbie Pritt, Center for Individualized Medicine, COVID-19, Department of Laboratory Medicine and Pathology, Dietrich Matern, Elitza Theel, genetics, genomics, John Mills


August 28, 2020

Mayo Clinic Research in the news — COVID, COVID, COVID

By Elizabeth Zimmermann Elizabeth Zimmermann

There has been a lot of discussion surrounding convalescent plasma in the last week. A few articles are listed here, an internet search will give you dozens more. In addition to convalescent plasma, our researchers are working on tests, vaccines, social and population health issues relating to COVID-19. Recent news articles highlighting Mayo Clinic Research […]

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Tags: Angela Mattke, cardiology, COVID-19, emergency department, genomics, Gregory Poland, health disparities, immunization, infection control, infectious disease, LaPrincess Brewer, Michael Ackerman


February 18, 2020

Mayo researchers studying ‘promising’ new approach to treating advanced cancer, 1 patient at a time, 1 tumor at a time

By Susan Murphy Susan Murphy

A collaborative team of Mayo Clinic scientists is studying an innovative strategy for treating advanced cancer, using genomics and human tumor samples as their guide. The novel approach, called Ex Vivo, creates a miniature cancer replica for testing therapies outside a patient’s body, combined with a comprehensive genomic analysis of a patient’s cancer cells. “We […]

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Tags: biomarkers, cancer, cancer genomics, Center for Individualized Medicine, genomics, George Vasmatzis, individualized medicine, Mayo Clinic Cancer Center, Minetta Liu, Panos Anastasiadis, personalized medicine


January 9, 2020

In a first, researchers sequence single bacterial cells, paving path for rapid sepsis test

By Susan Murphy Susan Murphy

For the first time, Mayo Clinic researchers are sequencing the genomic contents of single bacterial cells. The technique may pave the way for a potential lifesaving test for sepsis, a serious and sometimes deadly condition caused by the body’s response to an infection. Rather than waiting for days to identify the source of a patient’s […]

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Tags: antibacterial resistance, basic science, biomedical engineering, Center for Individualized Medicine, deep space medicine, genomics, Heidi Nelson, infectious disease, Marina Walther-Antonio, Nicholas Chia, Robin Patel, sepsis


November 14, 2019

Late relapse for breast cancer patients: Scientists work to predict risk

By Advancing the Science contributor Advancing the Science contributor

By Sara Nick Many breast cancer patients develop recurrence years after the original diagnosis, despite following a long-term medication protocol after initial treatment. Mayo Clinic scientists are taking a closer look at which factors contribute to risk of recurrence, including the subtype of cancer patients have. “Understanding which patients are still at risk of late […]

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Tags: breast cancer, E. Aubrey Thompson, genomics, Mayo Clinic Cancer Center, Saranya Chumsri


November 6, 2019

Precision genomics may offer clues to unexplained low blood cell counts

By Advancing the Science contributor Advancing the Science contributor

By Jay Furst Precision genomics has opened the door to identifying the drivers for cancer and other diseases. Its value as a diagnostic tool isn’t limited to the underlying disease biology, however. It also can help diagnose and determine targeted therapies for patients with unexplained illnesses. Mrinal Patnaik, M.B.B.S., a Mayo Clinic hematologist, and colleagues […]

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Tags: blood cancer, Center for Individualized Medicine, genomics, hematology, Mayo Clinic Proceedings, Mrinal Patnaik, precision medicine


October 14, 2019

BEAUTY Update: Progress in breast cancer research

By Advancing the Science contributor Advancing the Science contributor

By Barbara J. Toman Chemotherapy is a standard breast cancer treatment, used for aggressive biology breast cancer to shrink tumors in the breast and lymph nodes before surgery, assess response and destroy any undetected cancer cells elsewhere in the patient. But some breast tumors don’t respond well to chemotherapy, putting patients at high risk of […]

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Tags: breast cancer, cancer, Center for Individualized Medicine, chemotherapy, clinical trials, genetics, genomics, individualized medicine, Judy Boughey, Liewei Wang, Matthew Goetz, Mayo Clinic Cancer Center


September 18, 2019

Genomics and computer science intersect to improve patient care

By Advancing the Science contributor Advancing the Science contributor

By Sharon Rosen Computational genomics is a field that brings high-performance computing resources to drive precision medicine research toward new discoveries. However, when over 50 Mayo Clinic physicians, researchers and students gathered in June to participate in the Computational Genomics Course, the emphasis was on the needs of the patient. The annual week-long intensive course […]

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Tags: Center for Individualized Medicine, education, epigenetics, genomics, Justin Nguyen, Nidhi Jalan Sakrikar, research education, Timothy Curry, University of Illinois Urbana-Champaign


September 11, 2019

Targeting therapy to each patient’s unique cancer

By Advancing the Science contributor Advancing the Science contributor

Article by Sara Damore As DNA sequencing technology helps bring genetic factors driving disease into focus, researchers have developed new cancer therapies to target a patient’s unique cancer, especially for those who do not respond to standard therapy. Funda Meric-Bernstam, M.D., a physician-scientist at MD Anderson Cancer Center, will speak on Decision Support  for Precision […]

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Tags: Alan Bryce, cancer, Center for Individualized Medicine, clinical trials, DNA, genomics, hematology, Mayo Clinic Cancer Center, oncology, personalized medicine


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