November 24, 2020 · Leave a Comment
3D brain models advance Alzheimer’s disease research at Mayo Clinic
A 3D model of brain organoids — “a minibrain in a dish” — mimics human brain structure and provides a new scientific strategy for exploring the pathology of Alzheimer’s disease, Mayo Clinic research discovered. The study, which was published in Nature Communications, finds that the minibrain — an induced pluripotent stem cell-derived cerebral organoid 3D […]
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Tags: Alzheimer's disease, Center for Regenerative Medicine, Guojun Bu, medical research, neurosciences
September 17, 2020 · Leave a Comment
Could regenerative medicine hold a key to understanding Alzheimer’s disease?
September is World Alzheimer’s Month, a time to raise awareness of research to unlock scientific mysteries around a disease that robs people of their memory, independence and ultimately their ability to think and reason. Focused on disease causes and cures, the Center for Regenerative Medicine is driving innovation as a collaborative partner in Mayo Clinic’s […]
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Tags: Alzheimer's disease, basic science, Center for Regenerative Medicine, dementia, discovery research, Guojun Bu, Melissa Murray, neurology, neurosciences, stem cells
May 1, 2020 · Leave a Comment
Non-COVID research in the news, 5/1/2020
By Advancing the Science contributor
Although the week’s coverage has largely consisted of COVID-19 news, closer inspection finds it peppered with Mayo Clinic research on some other topics. We’ve collected a few of the news clips for ease of review. Read on for findings in cancer, deep vein thrombosis and Alzheimer’s disease: cfDNA Assay Shows Predictive Value in Detecting Cancer, […]
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Tags: Alzheimer's disease, cancer, cancer genomics, David Thiel, deep vein thrombosis, DNA, Guojun Bu, News of the Week, Rosa Rademakers
October 9, 2018 · Leave a Comment
Often people with diabetes have brain changes that are hallmarks of both Alzheimer’s disease and vascular dementia. Some researchers believe that each condition fuels the damage caused by the other. That link may occur as a result of the ways that type 2 diabetes affects the ability of the brain and other body tissues to […]
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Tags: Alzheimer's disease, Center for Regenerative Medicine, diabetes, endocrinology, gene therapy, Guojun Bu, stem cells
July 24, 2018 · Leave a Comment
Mayo scientists presenting at Alzheimer’s Association conference
About 30 Mayo Clinic scientists are presenting at this week’s Alzheimer’s Association International Conference in Chicago, and another roughly two dozen researchers are contributing authors. They’re among more than 5,600 scientists from 65 countries. The schedule and abstracts are available on the Alzheimer’s Association conference website. All the research has one goal: to help the growing […]
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Tags: Alzheimer's disease, David Knopman, David T. Jones, Guojun Bu, Kejal Kantarci, Mayo Clinic Study of Aging, Prashanthi Vemuri, Rochester Epidemiology Project, Ronald Petersen
October 10, 2017 · Leave a Comment
Researchers Link Alzheimer’s Gene to Type III Diabetes
By Kate Ledger
Researchers have known for several years that being overweight and having Type II diabetes can increase the risk of developing Alzheimer’s disease. But they’re now beginning to talk about another form of diabetes—Type III diabetes—that’s also associated with the neurodegenerative disease. This newly defined diabetes occurs when the neurons in the brain become unable to […]
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Tags: Alzheimer's disease, Chia-Chen Liu, diabetes, Guojun Bu, Na Zhao, Yuka Martens
October 3, 2017 · Leave a Comment
Alzheimer’s Researcher Receives MERIT Award
Neuroscientist Guojun Bu, Ph.D., Mary Lowell Leary Professor of Medicine, on Mayo Clinic’s campus in Florida, has been selected to receive the prestigious Method to Extend Research in Time (MERIT) Award. Granted by the National Advisory Council on Aging, the award provides long-term research funding to outstanding principal investigators who have demonstrated success on projects […]
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Tags: Alzheimer's disease, Guojun Bu, NIH, Tushar Patel