December 29, 2022
As we count down to 2023, the time is right to recap some of the hot topics of the last year. Spots 9 and 10 were occupied by three stories, so we went with the top 11. If you’re short on time as well as conversation starters, these articles could provide just the thing you […]
Tags: artificial intelligence, big data, biomedical research, Center for Individualized Medicine, Center for the Science of Health Care Delivery, COVID-19, diagnostic odyssey, DNA, environment, epidemiology, genetic testing, gut health
November 24, 2022
The future will be personalized: Accelerating microbiome research
By Advancing the Science contributor
We’re in the midst of a microbiome research epidemic, according to Purna Kashyap, M.B.B.S., co-associate director of the Microbiome Program in the Mayo Clinic Center for Individualized Medicine. “We started early and are pushing hard,” says Dr. Kashyap. “We’re one of the top accelerators in the field and are well poised to move microbiome research findings to […]
Tags: arthritis, C. diff, cancer, Center for Individualized Medicine, colitis, colorectal cancer, diabetes, endometrial cancer, Francis Farraye, gastroenterology, gut health, gynecology
March 23, 2022
By Susan Murphy
A growing number of people are dying from antibiotic-resistant infections. These infections are fueled by microbial species that are mutating to evade the drugs developed to destroy them. More than 1.2 million people worldwide died in 2019 from antibiotic-resistant infections. In response, a team of researchers from Mayo Clinic’s Center for Individualized Medicine has developed a sequencing technology to […]
Tags: antibacterial resistance, antibiotic, Center for Individualized Medicine, DNA, Emma Whittle, genomics, gut health, infection, infectious disease, microbiome, RNA
November 10, 2021
Mayo researchers link gut microbiome to rheumatoid arthritis prognosis
By Susan Murphy
A significant indicator of whether a patient with rheumatoid arthritis will improve over the course of disease may lie in part in their gut, according to new research from Mayo Clinic’s Center for Individualized Medicine. The study, published in Genome Medicine, found that predicting a patient’s future rheumatoid arthritis prognosis could be possible by zeroing in […]
Tags: arthritis, basic science, Center for Individualized Medicine, genomics, gut health, Jaeyun Sung, John Davis III, medical research, microbiome, rheumatology
August 25, 2021
Mayo Clinic analysis shows how disease, diet, and genomics interact with gut virome
Mayo Clinic researchers published a comprehensive analysis of the gut virome in Gastroenterology, showing how disease, diet and genomics interact with the gut virome in irritable bowel syndrome. This common disorder affects the intestine and manifests as abdominal pain associated with constipation, diarrhea or both. The gut virome is one component of the microbiome (bacteria, fungi, viruses). […]
Tags: Center for Individualized Medicine, DNA, gastroenterology, genomics, gut health, IBS, irritable bowel syndrome, microbiome, Purna Kashyap
October 6, 2020
Mayo scientists develop mathematical index to distinguish healthy microbiome from diseased
By Susan Murphy
What causes some people to develop chronic diseases such as rheumatoid arthritis, cancer and metabolic syndrome while others stay healthy? A major clue could be found in their gut microbiome — the trillions of microbes living inside the digestive system that regulate various bodily functions. To utilize the huge population of tiny organisms as a […]
Tags: Center for Individualized Medicine, genomics, gut health, Jaeyun Sung, microbiome, multiple chronic conditions
September 23, 2020
Mayo researcher finds potential microbial pathway to treat IBS symptoms, lessen abdominal pain
By Susan Murphy
Mayo Clinic researchers have found new evidence linking the millions of bacteria residing in our digestive systems, known as the microbiome, to a network of factors that drive irritable bowel syndrome (IBS). The findings, published in the Sept. 10, 2020, issue of Cell, raise the possibility of targeting the newly discovered microbial pathways to improve debilitating symptoms […]
Tags: Center for Individualized Medicine, gastroenterology, gut health, irritable bowel syndrome, microbiome, Purna Kashyap
November 1, 2019
A ‘gut-feeling’ for high-risk, high-reward research
Arthur Beyder, M.D., Ph.D., runs a research laboratory at Mayo Clinic focused on examining the molecular mechanisms of gastrointestinal function and dysfunction in diseases such as irritable bowel syndrome. His goal is to discover better ways to diagnose and treat these conditions, including individualized treatment options.
Tags: Arthur Beyder, gastroenterology, Gianrico Farrugia, gut health, IBS, irritable bowel syndrome
October 16, 2019
Advances in IBS Research Target Dietary Burdens
By Advancing the Science contributor
By Sara Nick The number one reason to miss school or work in the U.S. is the common cold. Number two? Irritable bowel syndrome (IBS), a disorder of the large intestine that can cause cramping, pain, gas, constipation, and diarrhea. “IBS is incredibly prevalent, affecting about 1 in 7 adults,” says Mayo Clinic gastroenterologist […]
Tags: Brian Lacy, gastroenterology, gut health, IBS, irritable bowel syndrome