Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘hematology’

November 24, 2022

The future will be personalized: Accelerating microbiome research

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

We’re in the midst of a microbiome research epidemic, according to Purna Kashyap, M.B.B.S., co-associate director of the Microbiome Program in the Mayo Clinic Center for Individualized Medicine. “We started early and are pushing hard,” says Dr. Kashyap. “We’re one of the top accelerators in the field and are well poised to move microbiome research findings to […]

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Tags: arthritis, C. diff, cancer, Center for Individualized Medicine, colitis, colorectal cancer, diabetes, endometrial cancer, Francis Farraye, gastroenterology, gut health, gynecology


October 11, 2022

Meet Surbhi Shah, M.B.B.S., M.D. – Driven to learn, incorporating learning to improve care

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

Surbhi Shah, M.B.B.S., M.D., is a hematologist at Mayo Clinic in Arizona., whose focus is on treating patients with non-cancerous blood disorders. In addition to her clinical duties, Dr. Shah dedicates time both to learning, and to sharing what she learns – through teaching, mentoring, presentation and publication. To expand her own understanding and increase Mayo’s […]

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Tags: anticoagulant, blood disease, Center for the Science of Health Care Delivery, clinical research, Fadi Shamoun, hematology, hemophilia, Jennifer Ridgeway, Kern Health Care Delivery Scholars, learning health system, medical innovation, mentorship


September 27, 2022

Physician-scientist investigates dual CAR-T cell therapy for multiple myeloma cancer

By Susan Murphy Susan Murphy (@susanmurphy)

Leo Sakemura, M.D., Ph.D., a physician-scientist in Mayo Clinic’s Division of Hematology, is working to advance immunotherapy efficacy in multiple myeloma by uncovering treatment resistance mechanisms and developing a more potent immunotherapy approach. His strategy focuses on simultaneously targeting cancer cells and the ecosystem surrounding each tumor, known as the tumor microenvironment.  Dr. Sakemura’s previous […]

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Tags: cancer genomics, cancer research, CAR-T cell therapy, Center for Individualized Medicine, hematology, immunotherapy, Leo Sakemura, metabolomics, multiple myeloma


February 16, 2022

Mayo Clinic develops automated system to accelerate diagnoses for patients with rare diseases

By Susan Murphy Susan Murphy (@susanmurphy)

Mayo Clinic researchers are working to accelerate the diagnoses of rare diseases and renew hope for patients whose symptoms have defied an explanation ― sometimes for years or even decades.    The team of genomics experts has developed an automated system called RENEW for tracking new scientific knowledge from around the world of pathogenic genetic variants and […]

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Tags: Alejandro Ferrer, biomedical informatics, Center for Individualized Medicine, Eric Klee, genomics, hematology, rare disease


September 2, 2021

Understanding the inner workings of CAR-T therapy

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic researchers have biomanufactured chimeric antigen receptor-T cell therapy  (CAR-T cell therapy) in a new way to track the cells’ cancer fighting journey and predict toxic side effects. This Mayo Clinic breakthrough, published in Cancer Immunology Research, also could unravel the mystery of how to unleash CAR-T cell therapy to destroy solid tumors. “This […]

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Tags: CAR-T cell therapy, Center for Individualized Medicine, Center for Regenerative Medicine, chimeric antigen receptor therapy, clinical research, clinical trials, hematology, immunotherapy, Kah Whye Peng, Reona Sakemura, Saad Kenderian, Stephen Russell


August 10, 2021

Mayo Clinic Research in the news — 8/9/2021

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

COVID-19 has once again taken almost all the headlines. However, research and expertise across the vastness of medicine still continues. Those stories are at the top — dancing after menopause, hemp seeds for inflammation, ‘brain orgasms’, and more. Then read on for the latest understanding in why the delta variant spreads even among vaccinated people, […]

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Tags: Abinash Virk, Ala Dababneh, Angela Dispenzieri, antibodies, arthritis, Arya Mohabbat, cancer, cardiology, chemotherapy, COVID-19, dementia, Devang Sanghavi


April 5, 2021

Mayo Clinic Research in the news — 4/5/2021

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

Mayo Clinic research and faculty experts were featured in a variety of news stories including 3D printed surgical models, early treatment for smoldering multiple myeloma, and heart attacks in women. Updated guideline highlights new therapies, considerations in anaplastic thyroid cancer Healio, 4/1/2021 An updated guideline for best practices in managing anaplastic thyroid cancer stresses the […]

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Tags: 3D printing, Alfredo Quinones-Hinojosa, Alzheimer's disease, artificial intelligence, blood cancer, chronic kidney disease, Clifford Jack Jr., COVID-19, digital health, Eric Moore, genetic testing, genetics


March 10, 2021

Mayo Clinic physician cracks patient’s mysterious illness with epigenetics technology

By Susan Murphy Susan Murphy (@susanmurphy)

Kenneth Hobby assumed his fever, fatigue and aching pains on that day in May 2018 were from another bout of malaria. He was visiting Zambia in southern Africa — the stomping grounds of his childhood and a place where the mosquito-borne parasite is common. He had returned to the vast safari lands, as he often […]

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Tags: blood disease, Center for Individualized Medicine, DNA, epigenetics, genomics, hematology, Mrinal Patnaik, rare disease


March 1, 2021

Mayo Clinic Research in the news — 3/1/2021

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

Media coverage of Mayo Clinic research and expertise covered home cancer screening tests, youth vaping, several advancements in women’s health, COVID-19 and many other topics. Read on for excerpts and links to the articles. Health officials: “Youth vaping a serious issue”  KAAL, 2/25/2021 New findings show youth vaping in Minnesota is worse than many had […]

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Tags: addiction research, Alzheimer's disease, Aminah Jatoi, anaphylaxis, arthritis, basic science, bladder cancer, BRCA1, BRCA2, cancer screening, clinical research, cognitive impairment


February 22, 2021

Mayo Clinic Research in the news — 2/22/2021

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

Over the last week, Mayo Clinic researchers and expertise have been cited in wide range of news stories, from the ever present COVID-19 to telehealth, participation in cancer clinical trials, creatine supplements, artificial intelligence and more. Read on for headlines, excerpts and links. Telehealth research & key resources: Research findings American Medical Association, 2/19/2021 Telehealth […]

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Tags: Andrew Jagim, angioplasty, artificial intelligence, Bernard Gersh, blood pressure, Brian Pickering, cancer, CAR-T cell therapy, cardiology, cardiovascular medicine, clinical trials, COVID-19


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