December 27, 2022
Engineering tissue to strengthen underdeveloped hearts
Could cells taken from a small patch of skin become heart muscle and repair a rare congenital heart defect? It’s a scientific question that Timothy Nelson, M.D., Ph.D., and collaborators hope to answer for those born with an underdeveloped left heart chamber — a rare, complex condition known as hypoplastic left heart syndrome (HLHS). Discovering […]
Tags: cardiomyocytes, Center for Regenerative Biotherapeutics, congenital heart disease, hypoplastic left heart syndrome, induced pluripotent stem cells, Timothy Nelson
March 23, 2020
Collaboration brings innovative regenerative therapies to babies with rare heart defect
By Jen Schutz
A collaboration bringing together regional centers and advocacy groups to accelerate innovation and discovery is expanding, bringing clinical trials and expertise to more patients with Hypoplastic Left Heart Syndrome (HLHS) across the country. Led by Mayo Clinic’s Todd and Karen Wanek Family Program for HLHS, the collaboration began in 2017 and now has 10 members. Nine […]
Tags: Center for Regenerative Medicine, clinical trials, congenital heart disease, HLHS, hypoplastic left heart syndrome, pediatric cardiology, Tim Nelson
September 24, 2019
Research for infants with HLHS moves forward
By Jen Schutz
Hypoplastic left heart syndrome (HLHS) is a complex and rare heart defect present at birth in which the left side of a child’s heart is severely underdeveloped. At Mayo Clinic, physicians and researchers in the Todd and Karen Wanek Family Program for Hypoplastic Left Heart Syndrome are looking for ways to delay or even prevent heart failure for […]
Tags: Center for Regenerative Medicine, clinical trials, HLHS, hypoplastic left heart syndrome, pediatric cardiology, stem cells
August 15, 2019
HLHS consortium gives hope to babies with rare congenital heart defect
By Jen Schutz
Hypoplastic Left Heart Syndrome (HLHS) is a rare disease that affects approximately 1 of every 4,300 babies every year. HLHS is a congenital heart defect in which the left side of the heart is underdeveloped. It occurs during fetal growth when the baby’s heart is developing. Without immediate intervention after birth, 95% of infants with HLHS […]
Tags: Center for Regenerative Medicine, HLHS, hypoplastic left heart syndrome, regenerative medicine, research, stem cells, Timothy Nelson
July 25, 2019
Undergraduate students participate in Mayo research, develop careers, collaborations
By Advancing the Science contributor
Advancements in the field of medical research do not always follow a straight line. There are obstacles, challenges and questions that are seemingly unsolvable. When researchers reach an impasse, what can they do?
They can start with a new question. If everyone in the room is saying, “Yes, but …,” then it may be time to find someone who is asking, “Why not?”
That’s the genesis behind Innovative Minds Partnering to Advance Curative Therapies, known as IMPACT. The program brings together undergraduates from all fields of study and from colleges and universities around the Midwest. The students form teams, each with a faculty mentor, to form hypotheses for a single, shared research question.
Tags: hypoplastic left heart syndrome, Katherine Campbell, Mayo Clinic Health System, Timothy Nelson
May 1, 2019
Research News Roundup-April 2019
The Mayo Clinic Research News Roundup includes brief summaries and links to research news releases from the past month. It also connects readers to related resources. Read on for more information from Mayo Clinic Research. Mayo Clinic, other experts call for urgent focus on brain disease that mimics Alzheimer’s In collaboration with the University of Kentucky, the […]
Tags: advance directive, Andrea Cheville, cancer, cardiology, clinical trials, HLHS, hypoplastic left heart syndrome, Mark Truty, pancreatic cancer, quality of life, radiation therapy, Research News Roundup
December 13, 2018
By Advancing the Science contributor
In 2011, Jared Ausnehmer left his local hospital carrying the weight of an oxygen tank and the worry of what might come next. At age 21, he’d already defied the odds for those born with hypoplastic left heart syndrome, a birth defect in which the left side of the heart is underdeveloped or nonexistent. With […]
Tags: Andre Terzic, cardiology, Center for Regenerative Medicine, clinical trials, HLHS, hypoplastic left heart syndrome
July 30, 2018
At Mayo Clinic, research is integral to everything we do. We would be unable to offer the highest possible levels of care and continually improve the practice of medicine without research, and the education programs and processes that underpin our care. Our research web is actually just a section of Mayo Clinic’s internet presence, but today we’re sharing some […]
Tags: basic science, Center for Clinical and Translational Science, HLHS, hypoplastic left heart syndrome, Kristin Zhao
June 5, 2018
Research News Roundup-May 2018
The Mayo Clinic Research News Roundup includes brief summaries and links to research news releases from the past month. It also connects readers to related resources. Read on for more information from Mayo Clinic Research. News flash about hot flashes: They can last longer than you think Mayo Clinic study finds women are experiencing hot flashes, night […]
Tags: All of Us, atrial fibrillation, Center for Individualized Medicine, Center for the Science of Health Care Delivery, Eva Galanis, Gianrico Farrugia, HLHS, hypoplastic left heart syndrome, Judy Boughey, lung cancer, Matthew Goetz, Mayo Clinic Cancer Center