Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘immunotherapy’

September 27, 2022

Physician-scientist investigates dual CAR-T cell therapy for multiple myeloma cancer

By Susan Murphy Susan Murphy (@susanmurphy)

Leo Sakemura, M.D., Ph.D., a physician-scientist in Mayo Clinic’s Division of Hematology, is working to advance immunotherapy efficacy in multiple myeloma by uncovering treatment resistance mechanisms and developing a more potent immunotherapy approach. His strategy focuses on simultaneously targeting cancer cells and the ecosystem surrounding each tumor, known as the tumor microenvironment.  Dr. Sakemura’s previous […]

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Tags: cancer genomics, cancer research, CAR-T cell therapy, Center for Individualized Medicine, hematology, immunotherapy, Leo Sakemura, metabolomics, multiple myeloma


June 15, 2022

Research News Roundup — May 2022

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

In May, researchers from Mayo Clinic reported gains in understanding of the benefit of AI-enabled ECGs, including from wearable devices. They made strides towards more effective treatment of non-Hodgkin lymphoma and nonmetastatic gastroesophageal cancer. And in news many people can use, investigators report on the results of a survey linked to the Mayo Clinic Diet. […]

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Tags: AFib, artificial intelligence, atrial fibrillation, CAR-T cell therapy, Center for the Science of Health Care Delivery, clinical trials, cognitive impairment, EKG, electrocardiogram, esophageal cancer, gastric cancer, gastroesophageal cancer


June 14, 2022

Dawn’s journey: Overcoming a near-zero survival rate

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

Dawn Botsford was sitting in a chair at the hair salon in the fall of 2011 when her hairdresser commented on a spot on the top of her head. It was bug season in North Dakota, so Dawn didn’t think much of it. “When I told my hairdresser that, she said, ‘I really think you […]

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Tags: cancer, clinical trials, dermatology, Eric Moore, immunotherapy, Mayo Clinic Cancer Center, melanoma, oncology, Robert McWilliams, skin cancer, Stephen Cassivi, Svetomir Markovic


March 2, 2022

Research News Roundup — January, February 2022

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

At Mayo Clinic, researchers work across the spectrum of health care and disease, from basic discovery science to transformations in patient care. They translate early findings into therapeutic or preventive interventions via clinical research and innovative pilot projects. Mayo Clinic researchers publish thousands of articles in peer-reviewed journals each year. A fraction of those findings […]

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Tags: A. Noelle Larson, Andrew Bentall, animal model, anticoagulant, biomedical engineering, bone regeneration, cardiovascular disease, chemotherapy, cirrhosis, COVID-19, gastrointestinal cancer, health disparities


December 30, 2021

Research News Roundup — 2021 Q4

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

2021 has been another whirlwind year of COVID-19 related advances, so you might have missed all the other medical and health care delivery findings that have emerged. It would take more time than we both have to recap all the non-COVID-19 news from 2021, but if you read further, you’ll learn about some of Mayo […]

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Tags: arthritis, artificial intelligence, cancer, cancer screening, cardiology, cardiovascular medicine, clinical research, clinical trials, colorectal cancer, diabetes, dialysis, EKG


September 2, 2021

Understanding the inner workings of CAR-T therapy

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic researchers have biomanufactured chimeric antigen receptor-T cell therapy  (CAR-T cell therapy) in a new way to track the cells’ cancer fighting journey and predict toxic side effects. This Mayo Clinic breakthrough, published in Cancer Immunology Research, also could unravel the mystery of how to unleash CAR-T cell therapy to destroy solid tumors. “This […]

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Tags: CAR-T cell therapy, Center for Individualized Medicine, Center for Regenerative Medicine, chimeric antigen receptor therapy, clinical research, clinical trials, hematology, immunotherapy, Kah Whye Peng, Reona Sakemura, Saad Kenderian, Stephen Russell


June 28, 2021

Mayo Clinic Research in the news — 6/28/2021

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

Vaping, medical AI, the challenges of serving patients with cancer and diabetes, current COVID-19 vaccine and long haul information, and a wide selection of other topics are covered in this week’s news. The Vaping Study You Haven’t Heard Of Slate, 6/25/2021 A report from the Mayo Clinic looked at 70,000 patients and found no link […]

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Tags: Alzheimer's disease, antibodies, artificial intelligence, Ashley Wentworth, autoimmune disorder, Barbara Barry, bioethics, biomedical ethics, cancer, cardiovascular disease, Center for Regenerative Medicine, COVID-19


January 6, 2021

Diverse ways regenerative medicine is advancing health care

By Susan Buckles Susan Buckles (@susanbuckles)

Regenerative medicine has contributed to patient care in 2020 more than ever before, bolstered by synergies in research, practice and education. Mayo Clinic’s Center for Regenerative Medicine is at the forefront of a biotherapy revolution in which health care advances from treating disease to restoring health. “The centrality of the body to regenerate itself is […]

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Tags: 3D printing, Andre Terzic, artificial intelligence, Atta Behfar, autoimmune disorder, biomedical engineering, CAR-T cell therapy, Center for Regenerative Medicine, clinical research, clinical trials, data science, fetal surgery


January 5, 2021

Looking back on 2020: A successful year of research at Mayo Clinic in Florida

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

At Mayo Clinic, Research and Education provide the basis for all we are able to do for patients today. Furthermore, they enable practice transformation as we seek to meet future patient needs. From new capabilities in cell therapy and immunotherapy, to advances in neurodegenerative diseases and studies of the virus that causes COVID-19, research at Mayo Clinic continued […]

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Tags: Alzheimer's disease, Ben Pollock, biomanufacturing, biomarkers, biostatistics, brain, cancer, CAR-T cell therapy, carbon ion therapy, Center for Regenerative Medicine, chemotherapy, clinical research


August 11, 2020

Expanding CAR T-cell therapy, welcoming Dr. Qin

By Susan Buckles Susan Buckles (@susanbuckles)

The first time Hong Qin, M.D., Ph.D., saw images of how chimeric antigen receptor (CAR) T-cell therapy obliterated a tumor, he was captivated and inspired by this revolutionary treatment. As the new director of Regenerative Immunotherapies at Mayo Clinic in Florida, Dr. Qin and his team will play a pivotal role in accelerating the latest […]

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Tags: blood cancer, CAR-T cell therapy, Center for Regenerative Medicine, Hong Qin, immunotherapy, leukemia, Mayo Clinic Cancer Center, regenerative medicine


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