Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘induced pluripotent stem cells’

February 7, 2023

Reprogramming stem cells to heal disease

By Susan Buckles Susan Buckles (@susanbuckles)

At one point, Shinya Yamanaka, M.D., Ph.D., was so down and discouraged that he almost gave up his research into embryonic cells and their powerful potential to replace diseased cells. He was finding little interest among colleagues; funding was hard to come by; and research journals rejected his studies. Then, discovery of human embryonic cell […]

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Tags: Center for Regenerative Biotherapeutics, induced pluripotent stem cells, Mayo Clinic Symposium on Regenerative Medicine & Surgery, reprogramming cells, Shinya Yamanaka

December 27, 2022

Engineering tissue to strengthen underdeveloped hearts

By Susan Buckles Susan Buckles (@susanbuckles)

Could cells taken from a small patch of skin become heart muscle and repair a rare congenital heart defect? It’s a scientific question that Timothy Nelson, M.D., Ph.D., and collaborators hope to answer for those born with an underdeveloped left heart chamber — a rare, complex condition known as hypoplastic left heart syndrome (HLHS). Discovering […]

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Tags: cardiomyocytes, Center for Regenerative Biotherapeutics, congenital heart disease, hypoplastic left heart syndrome, induced pluripotent stem cells, Timothy Nelson

September 22, 2020

Regenerative Medicine Biotrust: advancing the practice through research

By Susan Buckles Susan Buckles (@susanbuckles)

Regenerative medicine is a catalyst for innovation in health care, shifting the focus from treating symptoms of disease to unleashing the body’s ability to heal. Integral to the Mayo Clinic Center for Regenerative Medicine, the Center for Regenerative Medicine Biotrust is an important investment for Mayo Clinic. This unique resource enables physicians and scientists to […]

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Tags: Center for Regenerative Medicine, Dennis Wigle, induced pluripotent stem cells, Michael Ackerman, regenerative sciences, stem cell research, Zachary Resch

July 28, 2020

Using stem cells to find causes and treatments to prevent sudden cardiac death

By Susan Buckles Susan Buckles (@susanbuckles)

Mystified by the need for defibrillation to save a 10-year-old from drowning, Michael Ackerman, M.D., Ph.D., vowed to dig for answers. That pivotal case during a Mayo Clinic pediatric cardiology residency was the catalyst for Dr. Ackerman’s career in genetic sleuthing of inherited sudden cardiac death syndromes. With help from the Center for Regenerative Medicine […]

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Tags: Brugada syndrome, Center for Regenerative Medicine, hypertrophic cardiomyopathy, induced pluripotent stem cells, long QT syndrome, Michael Ackerman, regenerative medicine, sudden cardiac death

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