Items Tagged ‘Kent Arrell’
July 19, 2022
Molecular mapping of the heart to predict disease susceptibility
Vulnerability to heart disease can be projected before symptoms occur, Mayo Clinic discovered in preclinical research. This proof-of-concept study revealed that heart muscle changes indicate who is vulnerable to disease later in life. These changes can be detected from blood samples through comprehensive protein and metabolite profiling. This exploratory mapping, conducted in the Marriott Family […]
Tags: Andre Terzic, cardiac regeneration, Center for Regenerative Medicine, heart disease, Kent Arrell, Marriott Family Comprehensive Cardiac Regenerative Program, multiomics, Satsuki Yamada
July 12, 2021
Demystifying healing potential of stem cells
Mayo Clinic research has discovered proteins secreted by human stem cells that act as a “magic potion” to drive healing after a heart attack. The research uncovered that these cell-released regenerative particles harbor a pattern of functions mirrored in repair of the diseased heart, linking stem cell-transmitted information to the beneficial response of the recipient […]
Tags: Andre Terzic, cardiopoietic stem cells, Center for Regenerative Medicine, heart attack, heart disease, heart failure, Kent Arrell, stem cell therapy
April 16, 2020
Mayo Clinic research discovers how stem cells repair damage from heart attacks
Mayo Clinic researchers have uncovered stem cell-activated mechanisms of healing after a heart attack. Stem cells restored cardiac muscle back to its condition before the heart attack, in turn providing a blueprint of how stem cells may work. The study, published in NPJ Regenerative Medicine, finds that human cardiopoietic cells zero in on damaged proteins to reverse […]
Tags: Andre Terzic, basic science, cardiac regeneration, cardiovascular disease, Center for Regenerative Medicine, discovery research, heart attack, heart failure, Kent Arrell, mesenchymal stem cells, stem cells