Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘Center for Individualized Medicine’

March 21, 2019

Colon cancer: a new era in cancer screening and detection

By Susan Buckles susanbuckles

March is Colorectal Cancer Awareness Month, a time to focus on one of the most common and preventable forms of cancer. Mayo Clinic is applying a new genomic lens to colorectal and other cancers to identify which are the types that run in families. The answer to that could open new treatment options and also […]

View full entry

Tags: cancer genomics, Center for Individualized Medicine, colon cancer, hereditary cancer, Lynch syndrome, Niloy "Jewel" Samadder, precision medicine


March 7, 2019

What do Yellowstone rocks teach us about kidney stones

By Susan Buckles susanbuckles

This article originally appeared on the Center for Individualized Medicine blog. Mayo Clinic researchers are turning to Yellowstone National Park to unlock the secrets of kidney stones. Medical science long has been mystified by a cause and cure for this painful condition that affects more than 1 in 10 Americans. Mayo Clinic Center for Individualized […]

View full entry

Tags: Center for Individualized Medicine, kidney stones, medical research, microbiome, Nicholas Chia


February 21, 2019

Probiotics: One size does not fit all

By Susan Buckles susanbuckles

This article originally appeared on the Center for Individualized Medicine blog The allure of probiotics can be hard to resist. Popular belief holds that when you take probiotics in pill, powder or food, you boost your gut health with a powerful antidote to digestive diseases. But what exactly are probiotics, and how do you separate truth […]

View full entry

Tags: Center for Individualized Medicine, gut health, microbiome, probiotics, Purna Kashyap


February 14, 2019

Using brain organoids to uncover causes of neuropsychiatric disorders

By Colette Gallagher colettegallagher

Mayo Clinic and Yale University collaborated in a study published in Science to create a new model for studying neuropsychiatric disorders in early human brain development. This unique collaboration brought together Mayo Clinic’s team-based, patient-centered research with Yale researchers to discover and analyze the genetic mechanisms that may cause these disorders. The Mayo Clinic team, […]

View full entry

Tags: Alexej Abyzov, autism, Center for Individualized Medicine


February 12, 2019

Mayo Clinic discovery advances potential individualized treatment for mesothelioma

By Susan Buckles susanbuckles

Large chromosomal rearrangements present in mesothelioma could make it possible to understand which patients are likely respond to immunotherapy,  researchers at the Mayo Clinic Center for Individualized Medicine  have discovered. The research is published in the Journal of Thoracic Oncology. “What we’ve shown so far is that these large complex chromosomal rearrangements are frequent in […]

View full entry

Tags: Aaron Mansfield, basic science, cancer, Center for Individualized Medicine, DNA, genomics, George Vasmatzis, immunology, Mayo Clinic Cancer Center, mesothelioma


January 22, 2019

Pharmacogenomics: finding the right drug, dose for cancer therapy

By Advancing the Science contributor advancingthescience

By Sharon Rosen Each year, nearly 300,000 patients receive the lifesaving chemotherapy 5-fluorouracil (5-FU) to treat many types of cancer, including colorectal, breast, bowel, skin, pancreatic, and esophageal cancer. While it can be an effective treatment, it doesn’t work for everyone. In fact, up to 30 percent of those who receive the standard dose can […]

View full entry

Tags: cancer, Center for Individualized Medicine, individualized medicine, Mayo Clinic Cancer Center, personalized medicine, pharmacogenomics, Robert Diasio


January 17, 2019

RIGHT 10K: Blazing a trail to health care’s future

By Susan Buckles susanbuckles

Article by Barbara Toman This article originally appeared on the Center for Individualized Medicine blog Mayo Clinic’s Center for Individualized Medicine (CIM) is nearing the finish line of the first stage of its unique RIGHT 10K study—an effort that doesn’t involve running shoes but nevertheless is paving the way to prescribing medications matched to a […]

View full entry

Tags: Center for Individualized Medicine, Eric Matey, genetics, Jessica Wright, pharmacogenomics, RIGHT 10K study


January 10, 2019

Gene therapy: potential and pitfalls

By Susan Buckles susanbuckles

Research is advancing gene therapy as a possible treatment or eventual cure for genetic diseases that bedevil modern science. Gene therapy was conceived over 20 years ago, and until recently, remained largely in the research lab. But gene therapy products are now beginning to be approved by the U.S. Food and Drug Administration for clinical […]

View full entry

Tags: Center for Individualized Medicine, David Deyle, gene mutation, gene therapy, Saad Kenderian


December 20, 2018

Discovery advances potential individualized treatment for mesothelioma

By Susan Buckles susanbuckles

This article originally ran on the Center for Individualized Medicine blog on November 26, 2018 Large chromosomal rearrangements present in mesothelioma could make it possible to understand which patients are likely respond to immunotherapy,  researchers at the Mayo Clinic Center for Individualized Medicine  have discovered. The research is published in the Journal of Thoracic Oncology. […]

View full entry

Tags: Aaron Mansfield, cancer, Center for Individualized Medicine, George Vasmatzis, mesothelioma


December 10, 2018

Novel data-driven approach for precision medicine

By Colette Gallagher colettegallagher

Thousands of patients’ tumors have been sequenced in the past decade, yielding a rich source of data on the changes associated with the cancer development and treatment response. However, there are no validated methods that are used in the clinic to select the best therapy. Today, Mayo Clinic researchers report an omics-guided (comprehensive) drug prioritization […]

View full entry

Tags: cancer, Center for Individualized Medicine, Judy Boughey, Krishna Rani Kalari, Liewei Wang, Matthew Goetz, personalized medicine, pharmacogenomics


Contact Us · Privacy Policy