Items Tagged ‘Center for Individualized Medicine’
July 21, 2021 · Leave a Comment
Mayo researchers develop algorithm to predict rheumatoid arthritis disease activity
By Susan Murphy 
Researchers within Mayo Clinic’s Center for Individualized Medicine and Division of Rheumatology have developed a first-of-its-kind machine learning algorithm that can predict rheumatoid arthritis disease activity in a patient. The algorithm analyzes biochemical metabolites ― the product of the body’s metabolism ― in blood. “Having fast, reliable and scalable measures for predicting the clinical course of disease […]
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Tags: arthritis, artificial intelligence, autoimmune disorder, biomarkers, Center for Individualized Medicine, clinical research, genomics, Jaeyun Sung, John Davis III, metabolism, metabolomics, rheumatology
July 20, 2021 · Leave a Comment
By Susan Murphy
Rochester, Minn. — Mayo Clinic researchers have discovered that genetic variants in a neuro-associated gene called SPTBN1 are responsible for causing a neurodevelopmental disorder. The study, published in Nature Genetics, is a first step in finding a potential therapeutic strategy for this disorder, and it increases the number of genes known to be associated with conditions that affect […]
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Tags: Center for Individualized Medicine, gene mutation, genetics, genomics, Margot Cousin, neurosciences
July 14, 2021 · Leave a Comment
Mayo Clinic research in the news — 7/12/2021
By Advancing the Science contributor
Research and expertise from Mayo Clinic have been in the news on topics from marijuana, sleep, disparities, dementia and doses of vaccine. Read more. New York Times, Can Marijuana Make You a Better Athlete? … “If you look at any test of physical performance, there’s either no data, it’s a wash, or marijuana makes it worse,” […]
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Tags: addiction research, alcoholism, Alejandro Rabinstein, Alyx Porter, Alzheimer's disease, artificial intelligence, autoimmune disorder, Bhanu Kolla, breast cancer, cancer vaccine, cardiology, Center for Individualized Medicine
July 14, 2021 · Leave a Comment
New Mayo study validates melanoma test to help some patients avoid surgical biopsy
By Susan Murphy
More than 100,00 people in the U.S. are expected to be diagnosed with melanoma this year — double the number of cases compared to 30 years ago, according to the American Academy of Dermatology Association. “Melanoma accounts for only about 2% of skin cancers, but it causes a majority of skin cancer deaths,” says Alexander Meves, M.D., a Mayo […]
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Tags: Alexander Meves, cancer, cancer genomics, Center for Individualized Medicine, melanoma, precision medicine
July 7, 2021 · Leave a Comment
Mayo researchers study genetic basis of high cholesterol in adults
In a new study published in NPJ Genomic Medicine, Mayo Clinic researchers found that genetic testing may help identify patients with high cholesterol, or hypercholesterolemia. It also may have implications for the clinical management of patients diagnosed with high cholesterol due to a genetic disorder, or familial hypercholesterolemia. “In our study, we found more than 50% of the […]
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Tags: Center for Individualized Medicine, cholesterol, genetic testing, hypercholesterolemia, Iftikhar Kullo, precision medicine
July 1, 2021 · Leave a Comment
Early cancer detection test studied at Mayo Clinic is introduced nationally
Mayo Clinic today recognized the debut of a groundbreaking multi-cancer early cancer detection (MCED) test called Galleri™ that can detect more than 50 types of cancers[1] through a simple blood draw. The Galleri test is intended to complement U.S. guideline-recommended cancer screenings. Mayo Clinic Oncologist Minetta Liu, M.D. was involved in the development of the new test. […]
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Tags: blood test, cancer, Center for Individualized Medicine, precision medicine
June 29, 2021 · Leave a Comment
Gene fusion discovery in ultrarare tumor highlights potential therapeutic target
By Susan Murphy
A scientific investigation led by a team of researchers from Mayo Clinic’s Center for Individualized Medicine reveals that an ultrarare cancer called epithelioid trophoblastic tumor (ETT), which can develop in the uterus after conception, recurrently exhibits an abnormal fusion of two genes. This fusion creates an unusual protein that triggers aggressive cell growth — the […]
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Tags: cancer genomics, Center for Individualized Medicine, precision medicine, rare disease, uterine cancer
June 8, 2021 · Leave a Comment
In the near future, genome sequencing, among other biological measures, will be as routine as X-rays and cholesterol testing. The challenge, though, will be accurately interpreting the vast amount of data and effectively using it to guide decisions about health care. In a position statement published in Hepatology, Mayo Clinic researchers layout perspectives of various stakeholders […]
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Tags: Arjun Athreya, artificial intelligence, big data, bioethics, Center for Individualized Medicine, data science, genetic testing, genetics, genomics, Konstantinos Lazaridis, patient experience, population health
April 22, 2021 · Leave a Comment
Mayo researchers reveal gene therapy path for treating children with rare, fatal genetic disease
By Susan Murphy
A gene therapy strategy developed by Mayo Clinic researchers could offer a potential treatment for a rare and fatal genetic disease that often sickens babies in their first days of life. The disease, propionic acidemia, occurs in 1 in 100,000 live births in the U.S. There is no cure. “As soon as the babies start […]
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Tags: Center for Individualized Medicine, gene therapy, genomics, precision medicine, rare disease
April 20, 2021 · Leave a Comment
Mayo researchers use AI to reveal causes of complex diseases
By Susan Murphy
Researchers within Mayo Clinic’s Center for Individualized Medicine have developed an artificial intelligence (AI) platform that can uncover causal drivers and relationships embedded within complex biomedical data. Nicholas Chia, Ph.D., I. John Kalantari, Ph.D., and Kia Khezeli, Ph.D., recently tested their machine-learning framework, called Causal Relation and Inference Search Platform (CRISP) on multiomic colorectal cancer samples […]
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Tags: artificial intelligence, cancer, Center for Individualized Medicine, colorectal cancer, data science, genomics, I. John Kalantari, Kia Khezeli, microbiome, NASA, Nicholas Chia, rare disease