Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘Center for Individualized Medicine’

November 6, 2019

Precision genomics may offer clues to unexplained low blood cell counts

By Advancing the Science contributor Advancing the Science contributor

By Jay Furst Precision genomics has opened the door to identifying the drivers for cancer and other diseases. Its value as a diagnostic tool isn’t limited to the underlying disease biology, however. It also can help diagnose and determine targeted therapies for patients with unexplained illnesses. Mrinal Patnaik, M.B.B.S., a Mayo Clinic hematologist, and colleagues […]

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Tags: blood cancer, Center for Individualized Medicine, genomics, hematology, Mayo Clinic Proceedings, Mrinal Patnaik, precision medicine


October 14, 2019

BEAUTY Update: Progress in breast cancer research

By Advancing the Science contributor Advancing the Science contributor

By Barbara J. Toman Chemotherapy is a standard breast cancer treatment, used for aggressive biology breast cancer to shrink tumors in the breast and lymph nodes before surgery, assess response and destroy any undetected cancer cells elsewhere in the patient. But some breast tumors don’t respond well to chemotherapy, putting patients at high risk of […]

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Tags: breast cancer, cancer, Center for Individualized Medicine, chemotherapy, clinical trials, genetics, genomics, individualized medicine, Judy Boughey, Liewei Wang, Matthew Goetz, Mayo Clinic Cancer Center


October 7, 2019

An Artificial Intelligence Tool to Improve Pancreatic Cancer Outcomes

By Advancing the Science contributor Advancing the Science contributor

Article by Barbara Toman Only 9% of people with pancreatic cancer live for five years after diagnosis. “That is an abysmally low number, probably the worst in human cancers,” says Michael Wallace, M.D., a digestive disease specialist at the Mayo Clinic campus in Florida. “We want to get that rate substantially higher.” Artificial intelligence is […]

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Tags: artificial intelligence, cancer, cancer prevention, cancer screening, Center for Individualized Medicine, Center for the Science of Health Care Delivery, gastroenterology, genetic counseling, genetic testing, imaging, Michael Wallace, pancreatic cancer


September 23, 2019

Meet Mukesh Pandey, Ph.D. – developing a new drug to detect prostate cancer in its earliest stages

By Advancing the Science contributor Advancing the Science contributor

By Sharon Rosen With a background in organic chemistry, Mukesh Pandey, Ph.D., initially planned to work in the pharmaceutical industry developing medications. But after completing a post-doctoral research fellowship in radiology at Harvard Medical School, he chose to focus his skills on improving imaging technologies to better detect the first signs of disease. Now he is […]

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Tags: cancer screening, Center for Individualized Medicine, discovery research, imaging, Mukesh Pandey, prostate cancer, radiology, Timothy DeGrado, Val Lowe


September 18, 2019

Genomics and computer science intersect to improve patient care

By Advancing the Science contributor Advancing the Science contributor

By Sharon Rosen Computational genomics is a field that brings high-performance computing resources to drive precision medicine research toward new discoveries. However, when over 50 Mayo Clinic physicians, researchers and students gathered in June to participate in the Computational Genomics Course, the emphasis was on the needs of the patient. The annual week-long intensive course […]

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Tags: Center for Individualized Medicine, education, epigenetics, genomics, Justin Nguyen, Nidhi Jalan Sakrikar, research education, Timothy Curry, University of Illinois Urbana-Champaign


September 11, 2019

Targeting therapy to each patient’s unique cancer

By Advancing the Science contributor Advancing the Science contributor

Article by Sara Damore As DNA sequencing technology helps bring genetic factors driving disease into focus, researchers have developed new cancer therapies to target a patient’s unique cancer, especially for those who do not respond to standard therapy. Funda Meric-Bernstam, M.D., a physician-scientist at MD Anderson Cancer Center, will speak on Decision Support  for Precision […]

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Tags: Alan Bryce, cancer, Center for Individualized Medicine, clinical trials, DNA, genomics, hematology, Mayo Clinic Cancer Center, oncology, personalized medicine


September 4, 2019

Mayo experts provide insights into how genes affect medication response

By Advancing the Science contributor Advancing the Science contributor

By Sharon Rosen Pharmacogenomics – how a person’s genes affect medication response – is touching virtually every area of medical care.  Findings from the Mayo Clinic RIGHT study (Right Drug, Right Dose, Right Time–Using Genomic Data to Individualize Treatment) showed that 99% of participants had at least one genetic variant that may affect their response […]

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Tags: breast cancer, cancer, cancer genomics, Center for Individualized Medicine, Eric Matey, Lauren Cornell, mental health, Michael Shuh, neurology, opioids, pharmacogenomics, pharmacy


August 27, 2019

Community voices guide use of biobank samples in research

By Caitlin Doran Caitlin Doran

Mayo Clinic supports biobanks—large collections of patient biological samples—near each of its three campuses in Arizona, Florida, and Minnesota, with the goal of supporting research to broaden the understanding of health and disease.  Paired with each biobank, Mayo fields a community advisory board (CAB), whose members are recruited from the local community to help guide […]

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Tags: biobank, Center for Individualized Medicine, community engagement, Richard Sharp, Sangre Por Salud, Suzette Bielinski


August 14, 2019

Can BioBanks Help Close Gaps in Health Outcomes?

By Advancing the Science contributor Advancing the Science contributor

By Barbara J. Toman By definition, personalized medicine requires diversity. One-size-fits-all doesn’t work for every individual, especially members of groups that are medically underserved. In collaboration with Arizona State University and Mountain Park Health Center (MPHC) in Phoenix, Mayo Clinic’s Center for Individualized Medicine has created a biobank to enhance the diversity of Mayo’s medical research. Sangre Por Salud (Spanish for Blood […]

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Tags: biobank, Center for Individualized Medicine, diversity, health disparities, individualized medicine, personalized medicine, Richard Caselli, Sangre Por Salud


July 31, 2019

Identifying hereditary cancer risk: genetic testing can lead to better screening, earlier treatment

By Advancing the Science contributor Advancing the Science contributor

By Sharon Rosen Do you have family members who have been diagnosed with gastrointestinal, breast or ovarian cancer? According to a recent Mayo Clinic study, nearly 5% to 10% of these cancers can be hereditary. That’s why it is important to share your family medical history with your physician, who can determine if you and […]

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Tags: breast cancer, cancer, Center for Individualized Medicine, gastrointestinal cancer, genetic testing, hereditary cancer, Mayo Clinic Cancer Center, Mayo Clinic Proceedings, Niloy "Jewel" Samadder, ovarian cancer


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