Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘Center for Individualized Medicine’

March 24, 2020

Individualized care for psychiatric disorders — Mayo Clinic Biobank + genetic testing could pave the way

By Susan Murphy Susan Murphy

By Sharon Rosen Patients suffering from depression, anxiety and substance use disorders often search for years to find treatment. Studies have shown that during this time gap, patients’ symptoms worsen, increasing their risk for other chronic illnesses, shortened lifespan and poor quality of life. Mayo Clinic statistical geneticist Joanna Biernacka, Ph.D. and her colleagues are working to […]

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Tags: anxiety, biobank, Center for Individualized Medicine, depression, genetic testing, genetics, Joanna Biernacka, Mark Frye, psychiatry, substance abuse disorder


March 19, 2020

Mentorship program a ‘guiding star’ for astrobiologist-turned-microbiome-researcher

By Caitlin Doran Caitlin Doran

Marina Walther-Antonio, Ph.D., came to Mayo Clinic to help start the Center for Individualized Medicine’s microbiome research program. In her previous job at NASA, she had worked with mathematicians, engineers, geologists, psychologists, and even political scientists to try to detect life in outer space. Mayo recruited her to look for “aliens”—bacteria and other organisms—living in […]

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Tags: Andrea Mariani, Bill Cliby, bioethics, Center for Clinical and Translational Science, Center for Individualized Medicine, cervical cancer, endometrial cancer, health disparities, health equity, Heidi Nelson, human papillomavirus, Jim Maher


March 10, 2020

Patient’s premature aging symptoms tied to shorter DNA strands

By Colette Gallagher Colette Gallagher

At only 27-years-old, Morgan Cook recalls the days when she had an abundant amount of energy. “I would lift weights. I would do cardio. I would – you name it, I would do it. I was a lot more active,” says Cook. “I felt like I was able to do more things with friends. I […]

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Tags: Center for Individualized Medicine, DNA, genetic counseling, genetic testing, genetics, Mrinal Patnaik, rare disease, short telomere syndrome


February 18, 2020

Mayo researchers studying ‘promising’ new approach to treating advanced cancer, 1 patient at a time, 1 tumor at a time

By Susan Murphy Susan Murphy

A collaborative team of Mayo Clinic scientists is studying an innovative strategy for treating advanced cancer, using genomics and human tumor samples as their guide. The novel approach, called Ex Vivo, creates a miniature cancer replica for testing therapies outside a patient’s body, combined with a comprehensive genomic analysis of a patient’s cancer cells. “We […]

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Tags: biomarkers, cancer, cancer genomics, Center for Individualized Medicine, genomics, George Vasmatzis, individualized medicine, Mayo Clinic Cancer Center, Minetta Liu, Panos Anastasiadis, personalized medicine


February 5, 2020

“I Just Didn’t Understand”: On a Mission to Cure ALS

By Advancing the Science contributor Advancing the Science contributor

By Barbara J. Toman For Veronique Belzil, Ph.D., the fight against amyotrophic lateral sclerosis (ALS) is personal. In 2000, while working as a psychologist in Canada, she watched her husband’s uncle succumb to the disease. “The progression was so fast and his condition was so sad,” she says. “I just didn’t understand how this could […]

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Tags: ALS, amyotrophic lateral sclerosis, Center for Individualized Medicine, DNA, epigenetics, Lou Gehrig's disease, Veronique Belzil


January 24, 2020

The Compass offers direction on biomedical issues

By Advancing the Science contributor Advancing the Science contributor

By Jay Furst A compass, whether the old-fashioned kind in a brass case or the hands-free version on your dashboard, provides direction and helps you to find your way. The word’s Latin origin, though, is about more than navigation. It’s the root of the word “compassion,” which implies feeling, connectedness and presence. It’s that deeper […]

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Tags: biomedical ethics, Center for Clinical and Translational Science, Center for Individualized Medicine, Daniel Hall-Flavin, health humanities, Mayo Clinic Proceedings, research, Richard Sharp


January 9, 2020

In a first, researchers sequence single bacterial cells, paving path for rapid sepsis test

By Susan Murphy Susan Murphy

For the first time, Mayo Clinic researchers are sequencing the genomic contents of single bacterial cells. The technique may pave the way for a potential lifesaving test for sepsis, a serious and sometimes deadly condition caused by the body’s response to an infection. Rather than waiting for days to identify the source of a patient’s […]

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Tags: antibacterial resistance, basic science, biomedical engineering, Center for Individualized Medicine, deep space medicine, genomics, Heidi Nelson, infectious disease, Marina Walther-Antonio, Nicholas Chia, Robin Patel, sepsis


December 30, 2019

Research highlights from Florida – fruitful in 2019

By Advancing the Science contributor Advancing the Science contributor

Florida sunshine doesn’t just contribute to big, juicy oranges. In 2019, Florida was a hotbed of growth for Mayo Clinic Research, with 11.8% more funding leading to new capabilities such as ex vivo perfusion for lungs – leading to more available for transplant, and carbon ion therapy for cancer – currently not available to patients in the U.S. Read on for more on these and other practice transforming activities.

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Tags: artificial intelligence, biopsy, breast cancer, cancer, cancer vaccine, carbon ion therapy, Center for Individualized Medicine, clinical trials, ex vivo lung perfusion, immunology, Keith Knutson, lung cancer


December 16, 2019

New Integrated Clinical Studies Unit

By Advancing the Science contributor Advancing the Science contributor

It’s described by physicians and researchers as one of the most advanced clinical research units in the southeastern U.S. The new Frank and Marisa Martire Family Integrated Clinical Studies Unit (ICSU) recently opened at Mayo Clinic in Florida. The 12-bed unit, housed on the second floor of the Dorothy J. and Harry T. Mangurian Building, […]

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Tags: biomedical research, cancer, Center for Clinical and Translational Science, Center for Individualized Medicine, Charles Burger, clinical research, clinical trials, James Foran, Mayo Clinic Cancer Center, Tushar Patel


November 6, 2019

Precision genomics may offer clues to unexplained low blood cell counts

By Advancing the Science contributor Advancing the Science contributor

By Jay Furst Precision genomics has opened the door to identifying the drivers for cancer and other diseases. Its value as a diagnostic tool isn’t limited to the underlying disease biology, however. It also can help diagnose and determine targeted therapies for patients with unexplained illnesses. Mrinal Patnaik, M.B.B.S., a Mayo Clinic hematologist, and colleagues […]

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Tags: blood cancer, Center for Individualized Medicine, genomics, hematology, Mayo Clinic Proceedings, Mrinal Patnaik, precision medicine


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