Items Tagged ‘Center for Individualized Medicine’
March 21, 2019
Colon cancer: a new era in cancer screening and detection
March is Colorectal Cancer Awareness Month, a time to focus on one of the most common and preventable forms of cancer. Mayo Clinic is applying a new genomic lens to colorectal and other cancers to identify which are the types that run in families. The answer to that could open new treatment options and also […]
Tags: cancer genomics, Center for Individualized Medicine, colon cancer, hereditary cancer, Lynch syndrome, Niloy "Jewel" Samadder, precision medicine
March 7, 2019
What do Yellowstone rocks teach us about kidney stones
This article originally appeared on the Center for Individualized Medicine blog. Mayo Clinic researchers are turning to Yellowstone National Park to unlock the secrets of kidney stones. Medical science long has been mystified by a cause and cure for this painful condition that affects more than 1 in 10 Americans. Mayo Clinic Center for Individualized […]
Tags: Center for Individualized Medicine, kidney stones, medical research, microbiome, Nicholas Chia
February 21, 2019
Probiotics: One size does not fit all
This article originally appeared on the Center for Individualized Medicine blog The allure of probiotics can be hard to resist. Popular belief holds that when you take probiotics in pill, powder or food, you boost your gut health with a powerful antidote to digestive diseases. But what exactly are probiotics, and how do you separate truth […]
Tags: Center for Individualized Medicine, gut health, microbiome, probiotics, Purna Kashyap
February 14, 2019
Using brain organoids to uncover causes of neuropsychiatric disorders
Mayo Clinic and Yale University collaborated in a study published in Science to create a new model for studying neuropsychiatric disorders in early human brain development. This unique collaboration brought together Mayo Clinic’s team-based, patient-centered research with Yale researchers to discover and analyze the genetic mechanisms that may cause these disorders. The Mayo Clinic team, […]
Tags: Alexej Abyzov, autism, Center for Individualized Medicine
February 12, 2019
Mayo Clinic discovery advances potential individualized treatment for mesothelioma
Large chromosomal rearrangements present in mesothelioma could make it possible to understand which patients are likely respond to immunotherapy, researchers at the Mayo Clinic Center for Individualized Medicine have discovered. The research is published in the Journal of Thoracic Oncology. “What we’ve shown so far is that these large complex chromosomal rearrangements are frequent in […]
Tags: Aaron Mansfield, basic science, cancer, Center for Individualized Medicine, DNA, genomics, George Vasmatzis, immunology, Mayo Clinic Cancer Center, mesothelioma
January 22, 2019
Pharmacogenomics: finding the right drug, dose for cancer therapy
By Advancing the Science contributor 
By Sharon Rosen Each year, nearly 300,000 patients receive the lifesaving chemotherapy 5-fluorouracil (5-FU) to treat many types of cancer, including colorectal, breast, bowel, skin, pancreatic, and esophageal cancer. While it can be an effective treatment, it doesn’t work for everyone. In fact, up to 30 percent of those who receive the standard dose can […]
Tags: cancer, Center for Individualized Medicine, individualized medicine, Mayo Clinic Cancer Center, personalized medicine, pharmacogenomics, Robert Diasio
January 17, 2019
RIGHT 10K: Blazing a trail to health care’s future
Article by Barbara Toman This article originally appeared on the Center for Individualized Medicine blog Mayo Clinic’s Center for Individualized Medicine (CIM) is nearing the finish line of the first stage of its unique RIGHT 10K study—an effort that doesn’t involve running shoes but nevertheless is paving the way to prescribing medications matched to a […]
Tags: Center for Individualized Medicine, Eric Matey, genetics, Jessica Wright, pharmacogenomics, RIGHT 10K study
January 10, 2019
Gene therapy: potential and pitfalls
Research is advancing gene therapy as a possible treatment or eventual cure for genetic diseases that bedevil modern science. Gene therapy was conceived over 20 years ago, and until recently, remained largely in the research lab. But gene therapy products are now beginning to be approved by the U.S. Food and Drug Administration for clinical […]
Tags: Center for Individualized Medicine, David Deyle, gene mutation, gene therapy, Saad Kenderian
December 20, 2018
Discovery advances potential individualized treatment for mesothelioma
This article originally ran on the Center for Individualized Medicine blog on November 26, 2018 Large chromosomal rearrangements present in mesothelioma could make it possible to understand which patients are likely respond to immunotherapy, researchers at the Mayo Clinic Center for Individualized Medicine have discovered. The research is published in the Journal of Thoracic Oncology. […]
Tags: Aaron Mansfield, cancer, Center for Individualized Medicine, George Vasmatzis, mesothelioma
December 10, 2018
Novel data-driven approach for precision medicine
Thousands of patients’ tumors have been sequenced in the past decade, yielding a rich source of data on the changes associated with the cancer development and treatment response. However, there are no validated methods that are used in the clinic to select the best therapy. Today, Mayo Clinic researchers report an omics-guided (comprehensive) drug prioritization […]
Tags: cancer, Center for Individualized Medicine, Judy Boughey, Krishna Rani Kalari, Liewei Wang, Matthew Goetz, personalized medicine, pharmacogenomics