Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘microbiome’

April 20, 2021 · Leave a Comment

Mayo researchers use AI to reveal causes of complex diseases

By Susan Murphy Susan Murphy (@susanmurphy)

Researchers within Mayo Clinic’s Center for Individualized Medicine have developed an artificial intelligence (AI) platform that can uncover causal drivers and relationships embedded within complex biomedical data. Nicholas Chia, Ph.D., I. John Kalantari, Ph.D., and Kia Khezeli, Ph.D., recently tested their machine-learning framework, called Causal Relation and Inference Search Platform (CRISP) on multiomic colorectal cancer samples […]

View full entry Comment on this

Tags: artificial intelligence, cancer, Center for Individualized Medicine, colorectal cancer, data science, genomics, I. John Kalantari, Kia Khezeli, microbiome, NASA, Nicholas Chia, rare disease


October 26, 2020 · Leave a Comment

Mayo Clinic Research in the news — 10/26/2020

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

At Mayo Clinic, patient care is evidence-based, meaning research drives the practice of medicine. Our scientists and clinician researchers are at work across the spectrum of health and the delivery of health care, seeking better outcomes and enhanced experiences while managing the total costs of care. Curable dementia, pot and opioids, childcare during COVID-19, and […]

View full entry Comment on this

Tags: Alzheimer's disease, Andrew Badley, artificial intelligence, autoimmune disorder, biomarkers, cardiovascular medicine, Charles Adler, clinical research, clinical trials, COVID-19, David Knopman, dementia


October 6, 2020 · Leave a Comment

Mayo scientists develop mathematical index to distinguish healthy microbiome from diseased

By Susan Murphy Susan Murphy (@susanmurphy)

What causes some people to develop chronic diseases such as rheumatoid arthritis, cancer and metabolic syndrome while others stay healthy? A major clue could be found in their gut microbiome — the trillions of microbes living inside the digestive system that regulate various bodily functions. To utilize the huge population of tiny organisms as a […]

View full entry Comment on this

Tags: Center for Individualized Medicine, genomics, gut health, Jaeyun Sung, microbiome, multiple chronic conditions


October 2, 2020 · Leave a Comment

Mayo Clinic Research in the news — 10/2/2020

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

This week Mayo Clinic Research and researchers have been noted in stories on older women’s sexuality, the opioid crisis, some health benefits of coffee, using Alexa for COVID-19, and a range of other topics. Read on for links and brief excerpts from news outlets around the country. The Apple Watch heart monitor sends too many […]

View full entry Comment on this

Tags: Amir Lerman, artificial intelligence, B-cell disorders, biomarkers, C. diff, cancer, cardiology, colon cancer, COVID-19, diabetes, dogs, emergency medicine


September 29, 2020 · Leave a Comment

Study moves microbiome-based therapies closer to the mainstream treatment for C. difficile infection

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

A new study published online in the journal Clinical Infectious Diseases looked at the use of a non-frozen capsule of microbiome restoration therapy for treating patients with recurrent C. difficile infection. “Patients with C. difficile are typically managed with antibiotics or fecal transplantation for recurrent C. difficile,” says the study’s author, Sahil Khanna, M.B.B.S., a gastroenterologist at Mayo […]

View full entry Comment on this

Tags: C. diff, clinical trials, fecal transplant, gastroenterology, microbiome, Sahil Khanna


September 23, 2020 · Leave a Comment

Mayo researcher finds potential microbial pathway to treat IBS symptoms, lessen abdominal pain

By Susan Murphy Susan Murphy (@susanmurphy)

Mayo Clinic researchers have found new evidence linking the millions of bacteria residing in our digestive systems, known as the microbiome, to a network of factors that drive irritable bowel syndrome (IBS). The findings, published in the Sept. 10, 2020, issue of Cell, raise the possibility of targeting the newly discovered microbial pathways to improve debilitating symptoms […]

View full entry Comment on this

Tags: Center for Individualized Medicine, gastroenterology, gut health, irritable bowel syndrome, microbiome, Purna Kashyap


April 30, 2020 · Leave a Comment

Mayo researchers’ endometrial cancer discovery could lead to window of opportunity for prevention

By Susan Murphy Susan Murphy (@susanmurphy)

What if a doctor could alert a woman a year or more in advance that she is likely to develop endometrial cancer? Researchers at Mayo Clinic Center for Individualized Medicine have found evidence linking functional modification of certain genes to the emergence of the disease, providing a novel opportunity for intervention and prevention. The new […]

View full entry Comment on this

Tags: Andrea Mariani, biomarkers, cancer, Center for Individualized Medicine, endometrial cancer, epigenetics, gynecology, Marina Walther-Antonio, Mayo Clinic Cancer Center, microbiome, oncology, robotic technology


March 19, 2020 · Leave a Comment

Mentorship program a ‘guiding star’ for astrobiologist-turned-microbiome-researcher

By Caitlin Doran Caitlin Doran (@caityrosey)

Marina Walther-Antonio, Ph.D., came to Mayo Clinic to help start the Center for Individualized Medicine’s microbiome research program. In her previous job at NASA, she had worked with mathematicians, engineers, geologists, psychologists, and even political scientists to try to detect life in outer space. Mayo recruited her to look for “aliens”—bacteria and other organisms—living in […]

View full entry Comment on this

Tags: Andrea Mariani, Bill Cliby, bioethics, Center for Clinical and Translational Science, Center for Individualized Medicine, cervical cancer, endometrial cancer, health disparities, health equity, Heidi Nelson, human papillomavirus, Jim Maher


April 23, 2019 · Leave a Comment

Testing the bugs within to maintain health, detect and treat disease

By Susan Buckles Susan Buckles (@susanbuckles)

Article by Sharon Rosen The use of microbiome testing – which analyzes the trillions of bacteria in and on the body – is on the move. It’s going from the research lab into the clinic to help guide patient care. DNA testing technologies have revolutionized researchers’ ability to identify individual bacterial strains driving disease. Now […]

View full entry Comment on this

Tags: Center for Individualized Medicine, colorectal cancer, digestive diseases, DNA testing, gastroenterology, gut health, microbiome, Purna Kashyap


March 7, 2019 · Leave a Comment

What do Yellowstone rocks teach us about kidney stones

By Susan Buckles Susan Buckles (@susanbuckles)

This article originally appeared on the Center for Individualized Medicine blog. Mayo Clinic researchers are turning to Yellowstone National Park to unlock the secrets of kidney stones. Medical science long has been mystified by a cause and cure for this painful condition that affects more than 1 in 10 Americans. Mayo Clinic Center for Individualized […]

View full entry Comment on this

Tags: Center for Individualized Medicine, kidney stones, medical research, microbiome, Nicholas Chia


Contact Us · Privacy Policy