December 29, 2022
As we count down to 2023, the time is right to recap some of the hot topics of the last year. Spots 9 and 10 were occupied by three stories, so we went with the top 11. If you’re short on time as well as conversation starters, these articles could provide just the thing you […]
Tags: artificial intelligence, big data, biomedical research, Center for Individualized Medicine, Center for the Science of Health Care Delivery, COVID-19, diagnostic odyssey, DNA, environment, epidemiology, genetic testing, gut health
December 29, 2022
New tool brings Mayo Clinic researchers closer to discovering therapeutics from microbiome
By Susan Murphy
Does the human microbiome inhabit a natural pharmacy? Microorganisms are found in tissues and biofluids throughout the body, including in and around the gut, lungs, nose, mouth, skin and vagina. A flurry of recent scientific research suggests that this human microbiome — a community of trillions of bacteria, viruses and fungi — is a driver […]
Tags: Center for Individualized Medicine, Jaeyun Sung, microbiome
September 7, 2022
Nurse-scientist investigates gut microbiome link to chemotherapy-induced nausea
By Susan Murphy
Komal Singh, Ph.D., a nurse-scientist in Mayo Clinic’s Department of Nursing is investigating individualized strategies to help mitigate symptoms of chemotherapy-induced nausea in patients receiving chemotherapy for breast cancer. Her research focuses on the complex link between nausea-related symptoms and the gut microbiome — a population of bacteria, viruses, and fungi that inhabit the gastrointestinal tract. […]
Tags: Center for Individualized Medicine, chemotherapy, microbiome, multiomics
March 23, 2022
By Susan Murphy
A growing number of people are dying from antibiotic-resistant infections. These infections are fueled by microbial species that are mutating to evade the drugs developed to destroy them. More than 1.2 million people worldwide died in 2019 from antibiotic-resistant infections. In response, a team of researchers from Mayo Clinic’s Center for Individualized Medicine has developed a sequencing technology to […]
Tags: antibacterial resistance, antibiotic, Center for Individualized Medicine, DNA, Emma Whittle, genomics, gut health, infection, infectious disease, microbiome, RNA
November 10, 2021
Mayo researchers link gut microbiome to rheumatoid arthritis prognosis
By Susan Murphy
A significant indicator of whether a patient with rheumatoid arthritis will improve over the course of disease may lie in part in their gut, according to new research from Mayo Clinic’s Center for Individualized Medicine. The study, published in Genome Medicine, found that predicting a patient’s future rheumatoid arthritis prognosis could be possible by zeroing in […]
Tags: arthritis, basic science, Center for Individualized Medicine, genomics, gut health, Jaeyun Sung, John Davis III, medical research, microbiome, rheumatology
September 1, 2021
Uterine microbe found to have disease-causing behavior in endometrial cancer
By Susan Murphy
A tiny microbe thriving in the uterine microbiome — a population of bacteria, viruses, yeasts/fungi in and around the uterus— could be a contributing driver of endometrial cancer, according to a new Mayo Clinic study. “We have found that a microbe that is particularly associated with endometrial cancer is capable of pathogenic behavior, and is stimulated […]
Tags: Center for Individualized Medicine, endometrial cancer, Marina Walther-Antonio, microbiome, women's health
August 25, 2021
Mayo Clinic analysis shows how disease, diet, and genomics interact with gut virome
Mayo Clinic researchers published a comprehensive analysis of the gut virome in Gastroenterology, showing how disease, diet and genomics interact with the gut virome in irritable bowel syndrome. This common disorder affects the intestine and manifests as abdominal pain associated with constipation, diarrhea or both. The gut virome is one component of the microbiome (bacteria, fungi, viruses). […]
Tags: Center for Individualized Medicine, DNA, gastroenterology, genomics, gut health, IBS, irritable bowel syndrome, microbiome, Purna Kashyap
August 4, 2021
Researchers review how sex steroids change gut, vaginal microbiome
It is well-established that the human body’s microbiome ― the bacteria in the gut ― dramatically affects health and disease. However, the role of the gut in women’s health outcomes is largely unknown. Mayo Clinic and Wellesley College researchers focused on how the interactions of steroids on gut and vaginal microbiomes influence women’s health outcomes […]
Tags: Center for Individualized Medicine, genomics, Marina Walther-Antonio, microbiome
April 20, 2021
Mayo researchers use AI to reveal causes of complex diseases
By Susan Murphy
Researchers within Mayo Clinic’s Center for Individualized Medicine have developed an artificial intelligence (AI) platform that can uncover causal drivers and relationships embedded within complex biomedical data. Nicholas Chia, Ph.D., I. John Kalantari, Ph.D., and Kia Khezeli, Ph.D., recently tested their machine-learning framework, called Causal Relation and Inference Search Platform (CRISP) on multiomic colorectal cancer samples […]
Tags: artificial intelligence, cancer, Center for Individualized Medicine, colorectal cancer, data science, genomics, I. John Kalantari, Kia Khezeli, microbiome, NASA, Nicholas Chia, rare disease
October 26, 2020
Mayo Clinic Research in the news — 10/26/2020
At Mayo Clinic, patient care is evidence-based, meaning research drives the practice of medicine. Our scientists and clinician researchers are at work across the spectrum of health and the delivery of health care, seeking better outcomes and enhanced experiences while managing the total costs of care. Curable dementia, pot and opioids, childcare during COVID-19, and […]
Tags: Alzheimer's disease, Andrew Badley, artificial intelligence, autoimmune disorder, biomarkers, cardiovascular medicine, Charles Adler, clinical research, clinical trials, COVID-19, David Knopman, dementia