Items Tagged ‘microbiome’
November 10, 2021
Mayo researchers link gut microbiome to rheumatoid arthritis prognosis
By Susan Murphy 
A significant indicator of whether a patient with rheumatoid arthritis will improve over the course of disease may lie in part in their gut, according to new research from Mayo Clinic’s Center for Individualized Medicine. The study, published in Genome Medicine, found that predicting a patient’s future rheumatoid arthritis prognosis could be possible by zeroing in […]
Tags: arthritis, basic science, Center for Individualized Medicine, genomics, gut health, Jaeyun Sung, John Davis III, medical research, microbiome, rheumatology
September 1, 2021
Uterine microbe found to have disease-causing behavior in endometrial cancer
By Susan Murphy
A tiny microbe thriving in the uterine microbiome — a population of bacteria, viruses, yeasts/fungi in and around the uterus— could be a contributing driver of endometrial cancer, according to a new Mayo Clinic study. “We have found that a microbe that is particularly associated with endometrial cancer is capable of pathogenic behavior, and is stimulated […]
Tags: Center for Individualized Medicine, endometrial cancer, Marina Walther-Antonio, microbiome, women's health
August 25, 2021
Mayo Clinic analysis shows how disease, diet, and genomics interact with gut virome
Mayo Clinic researchers published a comprehensive analysis of the gut virome in Gastroenterology, showing how disease, diet and genomics interact with the gut virome in irritable bowel syndrome. This common disorder affects the intestine and manifests as abdominal pain associated with constipation, diarrhea or both. The gut virome is one component of the microbiome (bacteria, fungi, viruses). […]
Tags: Center for Individualized Medicine, DNA, gastroenterology, genomics, gut health, IBS, irritable bowel syndrome, microbiome, Purna Kashyap
August 4, 2021
Researchers review how sex steroids change gut, vaginal microbiome
It is well-established that the human body’s microbiome ― the bacteria in the gut ― dramatically affects health and disease. However, the role of the gut in women’s health outcomes is largely unknown. Mayo Clinic and Wellesley College researchers focused on how the interactions of steroids on gut and vaginal microbiomes influence women’s health outcomes […]
Tags: Center for Individualized Medicine, genomics, Marina Walther-Antonio, microbiome
April 20, 2021
Mayo researchers use AI to reveal causes of complex diseases
By Susan Murphy
Researchers within Mayo Clinic’s Center for Individualized Medicine have developed an artificial intelligence (AI) platform that can uncover causal drivers and relationships embedded within complex biomedical data. Nicholas Chia, Ph.D., I. John Kalantari, Ph.D., and Kia Khezeli, Ph.D., recently tested their machine-learning framework, called Causal Relation and Inference Search Platform (CRISP) on multiomic colorectal cancer samples […]
Tags: artificial intelligence, cancer, Center for Individualized Medicine, colorectal cancer, data science, genomics, I. John Kalantari, Kia Khezeli, microbiome, NASA, Nicholas Chia, rare disease
October 26, 2020
Mayo Clinic Research in the news — 10/26/2020
At Mayo Clinic, patient care is evidence-based, meaning research drives the practice of medicine. Our scientists and clinician researchers are at work across the spectrum of health and the delivery of health care, seeking better outcomes and enhanced experiences while managing the total costs of care. Curable dementia, pot and opioids, childcare during COVID-19, and […]
Tags: Alzheimer's disease, Andrew Badley, artificial intelligence, autoimmune disorder, biomarkers, cardiovascular medicine, Charles Adler, clinical research, clinical trials, COVID-19, David Knopman, dementia
October 6, 2020
Mayo scientists develop mathematical index to distinguish healthy microbiome from diseased
By Susan Murphy
What causes some people to develop chronic diseases such as rheumatoid arthritis, cancer and metabolic syndrome while others stay healthy? A major clue could be found in their gut microbiome — the trillions of microbes living inside the digestive system that regulate various bodily functions. To utilize the huge population of tiny organisms as a […]
Tags: Center for Individualized Medicine, genomics, gut health, Jaeyun Sung, microbiome, multiple chronic conditions
October 2, 2020
Mayo Clinic Research in the news — 10/2/2020
This week Mayo Clinic Research and researchers have been noted in stories on older women’s sexuality, the opioid crisis, some health benefits of coffee, using Alexa for COVID-19, and a range of other topics. Read on for links and brief excerpts from news outlets around the country. Laughter May Be Effective Medicine for These Trying […]
Tags: Amir Lerman, artificial intelligence, B-cell disorders, biomarkers, C. diff, cancer, cardiology, colon cancer, COVID-19, diabetes, dogs, emergency medicine
September 29, 2020
Study moves microbiome-based therapies closer to the mainstream treatment for C. difficile infection
By Advancing the Science contributor
A new study published online in the journal Clinical Infectious Diseases looked at the use of a non-frozen capsule of microbiome restoration therapy for treating patients with recurrent C. difficile infection. “Patients with C. difficile are typically managed with antibiotics or fecal transplantation for recurrent C. difficile,” says the study’s author, Sahil Khanna, M.B.B.S., a gastroenterologist at Mayo […]
Tags: C. diff, clinical trials, fecal transplant, gastroenterology, microbiome, Sahil Khanna
September 23, 2020
Mayo researcher finds potential microbial pathway to treat IBS symptoms, lessen abdominal pain
By Susan Murphy
Mayo Clinic researchers have found new evidence linking the millions of bacteria residing in our digestive systems, known as the microbiome, to a network of factors that drive irritable bowel syndrome (IBS). The findings, published in the Sept. 10, 2020, issue of Cell, raise the possibility of targeting the newly discovered microbial pathways to improve debilitating symptoms […]
Tags: Center for Individualized Medicine, gastroenterology, gut health, irritable bowel syndrome, microbiome, Purna Kashyap