Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘microbiome’

September 7, 2022

Nurse-scientist investigates gut microbiome link to chemotherapy-induced nausea

By Susan Murphy Susan Murphy (@susanmurphy)

Komal Singh, Ph.D., a nurse-scientist in Mayo Clinic’s Department of Nursing is investigating individualized strategies to help mitigate symptoms of chemotherapy-induced nausea in patients receiving chemotherapy for breast cancer. Her research focuses on the complex link between nausea-related symptoms and the gut microbiome — a population of bacteria, viruses, and fungi that inhabit the gastrointestinal tract.  […]

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Tags: Center for Individualized Medicine, chemotherapy, microbiome, multiomics


March 23, 2022

Nanopore sequencing method rapidly detects, identifies antibiotic-resistant microbes, Mayo Clinic research shows 

By Susan Murphy Susan Murphy (@susanmurphy)

A growing number of people are dying from antibiotic-resistant infections. These infections are fueled by microbial species that are mutating to evade the drugs developed to destroy them. More than 1.2 million people worldwide died in 2019 from antibiotic-resistant infections.  In response, a team of researchers from Mayo Clinic’s Center for Individualized Medicine has developed a sequencing technology to […]

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Tags: antibacterial resistance, antibiotic, Center for Individualized Medicine, DNA, Emma Whittle, genomics, gut health, infection, infectious disease, microbiome, RNA


November 10, 2021

Mayo researchers link gut microbiome to rheumatoid arthritis prognosis

By Susan Murphy Susan Murphy (@susanmurphy)

A significant indicator of whether a patient with rheumatoid arthritis will improve over the course of disease may lie in part in their gut, according to new research from Mayo Clinic’s Center for Individualized Medicine. The study, published in Genome Medicine, found that predicting a patient’s future rheumatoid arthritis prognosis could be possible by zeroing in […]

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Tags: arthritis, basic science, Center for Individualized Medicine, genomics, gut health, Jaeyun Sung, John Davis III, medical research, microbiome, rheumatology


September 1, 2021

Uterine microbe found to have disease-causing behavior in endometrial cancer

By Susan Murphy Susan Murphy (@susanmurphy)

A tiny microbe thriving in the uterine microbiome — a population of bacteria, viruses, yeasts/fungi in and around the uterus— could be a contributing driver of endometrial cancer, according to a new Mayo Clinic study.  “We have found that a microbe that is particularly associated with endometrial cancer is capable of pathogenic behavior, and is stimulated […]

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Tags: Center for Individualized Medicine, endometrial cancer, Marina Walther-Antonio, microbiome, women's health


August 25, 2021

Mayo Clinic analysis shows how disease, diet, and genomics interact with gut virome

By Colette Gallagher Colette Gallagher (@colettegallagher)

Mayo Clinic researchers published a comprehensive analysis of the gut virome in Gastroenterology, showing how disease, diet and genomics interact with the gut virome in irritable bowel syndrome. This common disorder affects the intestine and manifests as abdominal pain associated with constipation, diarrhea or both. The gut virome is one component of the microbiome (bacteria, fungi, viruses). […]

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Tags: Center for Individualized Medicine, DNA, gastroenterology, genomics, gut health, IBS, irritable bowel syndrome, microbiome, Purna Kashyap


August 4, 2021

Researchers review how sex steroids change gut, vaginal microbiome

By Colette Gallagher Colette Gallagher (@colettegallagher)

It is well-established that the human body’s microbiome ― the bacteria in the gut ― dramatically affects health and disease. However, the role of the gut in women’s health outcomes is largely unknown. Mayo Clinic and Wellesley College researchers focused on how the interactions of steroids on gut and vaginal microbiomes influence women’s health outcomes […]

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Tags: Center for Individualized Medicine, genomics, Marina Walther-Antonio, microbiome


April 20, 2021

Mayo researchers use AI to reveal causes of complex diseases

By Susan Murphy Susan Murphy (@susanmurphy)

Researchers within Mayo Clinic’s Center for Individualized Medicine have developed an artificial intelligence (AI) platform that can uncover causal drivers and relationships embedded within complex biomedical data. Nicholas Chia, Ph.D., I. John Kalantari, Ph.D., and Kia Khezeli, Ph.D., recently tested their machine-learning framework, called Causal Relation and Inference Search Platform (CRISP) on multiomic colorectal cancer samples […]

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Tags: artificial intelligence, cancer, Center for Individualized Medicine, colorectal cancer, data science, genomics, I. John Kalantari, Kia Khezeli, microbiome, NASA, Nicholas Chia, rare disease


October 26, 2020

Mayo Clinic Research in the news — 10/26/2020

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

At Mayo Clinic, patient care is evidence-based, meaning research drives the practice of medicine. Our scientists and clinician researchers are at work across the spectrum of health and the delivery of health care, seeking better outcomes and enhanced experiences while managing the total costs of care. Curable dementia, pot and opioids, childcare during COVID-19, and […]

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Tags: Alzheimer's disease, Andrew Badley, artificial intelligence, autoimmune disorder, biomarkers, cardiovascular medicine, Charles Adler, clinical research, clinical trials, COVID-19, David Knopman, dementia


October 6, 2020

Mayo scientists develop mathematical index to distinguish healthy microbiome from diseased

By Susan Murphy Susan Murphy (@susanmurphy)

What causes some people to develop chronic diseases such as rheumatoid arthritis, cancer and metabolic syndrome while others stay healthy? A major clue could be found in their gut microbiome — the trillions of microbes living inside the digestive system that regulate various bodily functions. To utilize the huge population of tiny organisms as a […]

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Tags: Center for Individualized Medicine, genomics, gut health, Jaeyun Sung, microbiome, multiple chronic conditions


October 2, 2020

Mayo Clinic Research in the news — 10/2/2020

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

This week Mayo Clinic Research and researchers have been noted in stories on older women’s sexuality, the opioid crisis, some health benefits of coffee, using Alexa for COVID-19, and a range of other topics. Read on for links and brief excerpts from news outlets around the country. Laughter May Be Effective Medicine for These Trying […]

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Tags: Amir Lerman, artificial intelligence, B-cell disorders, biomarkers, C. diff, cancer, cardiology, colon cancer, COVID-19, diabetes, dogs, emergency medicine


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