Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘microbiome’

September 1, 2021 · Leave a Comment

Uterine microbe found to have disease-causing behavior in endometrial cancer

By Susan Murphy Susan Murphy (@susanmurphy)

A tiny microbe thriving in the uterine microbiome — a population of bacteria, viruses, yeasts/fungi in and around the uterus— could be a contributing driver of endometrial cancer, according to a new Mayo Clinic study.  “We have found that a microbe that is particularly associated with endometrial cancer is capable of pathogenic behavior, and is stimulated […]

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Tags: Center for Individualized Medicine, endometrial cancer, Marina Walther-Antonio, microbiome, women's health


August 25, 2021 · Leave a Comment

Mayo Clinic analysis shows how disease, diet, and genomics interact with gut virome

By Colette Gallagher Colette Gallagher (@colettegallagher)

Mayo Clinic researchers published a comprehensive analysis of the gut virome in Gastroenterology, showing how disease, diet and genomics interact with the gut virome in irritable bowel syndrome. This common disorder affects the intestine and manifests as abdominal pain associated with constipation, diarrhea or both. The gut virome is one component of the microbiome (bacteria, fungi, viruses). […]

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Tags: Center for Individualized Medicine, DNA, genomics, microbiome, Purna Kashyap


August 4, 2021 · Leave a Comment

Researchers review how sex steroids change gut, vaginal microbiome

By Colette Gallagher Colette Gallagher (@colettegallagher)

It is well-established that the human body’s microbiome ― the bacteria in the gut ― dramatically affects health and disease. However, the role of the gut in women’s health outcomes is largely unknown. Mayo Clinic and Wellesley College researchers focused on how the interactions of steroids on gut and vaginal microbiomes influence women’s health outcomes […]

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Tags: Center for Individualized Medicine, genomics, Marina Walther-Antonio, microbiome


April 20, 2021 · Leave a Comment

Mayo researchers use AI to reveal causes of complex diseases

By Susan Murphy Susan Murphy (@susanmurphy)

Researchers within Mayo Clinic’s Center for Individualized Medicine have developed an artificial intelligence (AI) platform that can uncover causal drivers and relationships embedded within complex biomedical data. Nicholas Chia, Ph.D., I. John Kalantari, Ph.D., and Kia Khezeli, Ph.D., recently tested their machine-learning framework, called Causal Relation and Inference Search Platform (CRISP) on multiomic colorectal cancer samples […]

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Tags: artificial intelligence, cancer, Center for Individualized Medicine, colorectal cancer, data science, genomics, I. John Kalantari, Kia Khezeli, microbiome, NASA, Nicholas Chia, rare disease


October 26, 2020 · Leave a Comment

Mayo Clinic Research in the news — 10/26/2020

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

At Mayo Clinic, patient care is evidence-based, meaning research drives the practice of medicine. Our scientists and clinician researchers are at work across the spectrum of health and the delivery of health care, seeking better outcomes and enhanced experiences while managing the total costs of care. Curable dementia, pot and opioids, childcare during COVID-19, and […]

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Tags: Alzheimer's disease, Andrew Badley, artificial intelligence, autoimmune disorder, biomarkers, cardiovascular medicine, Charles Adler, clinical research, clinical trials, COVID-19, David Knopman, dementia


October 6, 2020 · Leave a Comment

Mayo scientists develop mathematical index to distinguish healthy microbiome from diseased

By Susan Murphy Susan Murphy (@susanmurphy)

What causes some people to develop chronic diseases such as rheumatoid arthritis, cancer and metabolic syndrome while others stay healthy? A major clue could be found in their gut microbiome — the trillions of microbes living inside the digestive system that regulate various bodily functions. To utilize the huge population of tiny organisms as a […]

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Tags: Center for Individualized Medicine, genomics, gut health, Jaeyun Sung, microbiome, multiple chronic conditions


October 2, 2020 · Leave a Comment

Mayo Clinic Research in the news — 10/2/2020

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

This week Mayo Clinic Research and researchers have been noted in stories on older women’s sexuality, the opioid crisis, some health benefits of coffee, using Alexa for COVID-19, and a range of other topics. Read on for links and brief excerpts from news outlets around the country. Laughter May Be Effective Medicine for These Trying […]

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Tags: Amir Lerman, artificial intelligence, B-cell disorders, biomarkers, C. diff, cancer, cardiology, colon cancer, COVID-19, diabetes, dogs, emergency medicine


September 29, 2020 · Leave a Comment

Study moves microbiome-based therapies closer to the mainstream treatment for C. difficile infection

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

A new study published online in the journal Clinical Infectious Diseases looked at the use of a non-frozen capsule of microbiome restoration therapy for treating patients with recurrent C. difficile infection. “Patients with C. difficile are typically managed with antibiotics or fecal transplantation for recurrent C. difficile,” says the study’s author, Sahil Khanna, M.B.B.S., a gastroenterologist at Mayo […]

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Tags: C. diff, clinical trials, fecal transplant, gastroenterology, microbiome, Sahil Khanna


September 23, 2020 · Leave a Comment

Mayo researcher finds potential microbial pathway to treat IBS symptoms, lessen abdominal pain

By Susan Murphy Susan Murphy (@susanmurphy)

Mayo Clinic researchers have found new evidence linking the millions of bacteria residing in our digestive systems, known as the microbiome, to a network of factors that drive irritable bowel syndrome (IBS). The findings, published in the Sept. 10, 2020, issue of Cell, raise the possibility of targeting the newly discovered microbial pathways to improve debilitating symptoms […]

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Tags: Center for Individualized Medicine, gastroenterology, gut health, irritable bowel syndrome, microbiome, Purna Kashyap


April 30, 2020 · Leave a Comment

Mayo researchers’ endometrial cancer discovery could lead to window of opportunity for prevention

By Susan Murphy Susan Murphy (@susanmurphy)

What if a doctor could alert a woman a year or more in advance that she is likely to develop endometrial cancer? Researchers at Mayo Clinic Center for Individualized Medicine have found evidence linking functional modification of certain genes to the emergence of the disease, providing a novel opportunity for intervention and prevention. The new […]

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Tags: Andrea Mariani, biomarkers, cancer, Center for Individualized Medicine, endometrial cancer, epigenetics, gynecology, Marina Walther-Antonio, Mayo Clinic Cancer Center, microbiome, oncology, robotic technology


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