March 10, 2021
Mayo Clinic physician cracks patient’s mysterious illness with epigenetics technology
By Susan Murphy
Kenneth Hobby assumed his fever, fatigue and aching pains on that day in May 2018 were from another bout of malaria. He was visiting Zambia in southern Africa — the stomping grounds of his childhood and a place where the mosquito-borne parasite is common. He had returned to the vast safari lands, as he often […]
Tags: blood disease, Center for Individualized Medicine, DNA, epigenetics, genomics, hematology, Mrinal Patnaik, rare disease
March 10, 2020
Patient’s premature aging symptoms tied to shorter DNA strands
At only 27-years-old, Morgan Cook recalls the days when she had an abundant amount of energy. “I would lift weights. I would do cardio. I would – you name it, I would do it. I was a lot more active,” says Cook. “I felt like I was able to do more things with friends. I […]
Tags: Center for Individualized Medicine, DNA, genetic counseling, genetic testing, genetics, Mrinal Patnaik, rare disease, short telomere syndrome
January 22, 2020
What’s Next for The Research of the Future
By Sara Tiner
Breakthroughs in medical science rarely burst on the scene. Behind every advance is years of work by dogged researchers who nurtured the seed of idea until it flowered, bore fruit and materialized into a better treatment, device or therapy for patients. Here is where those seeds start: More than a dozen projects related to cancer, […]
Tags: Anthony Windebank, basic science, cancer, cancer genomics, Center for Biomedical Discovery, Christopher Evans, Christopher Groen, Daniel Billadeau, Daniel Tschumperlin, discovery research, Eva Morava-Kozicz, fibrosis
November 6, 2019
Precision genomics may offer clues to unexplained low blood cell counts
By Advancing the Science contributor
By Jay Furst Precision genomics has opened the door to identifying the drivers for cancer and other diseases. Its value as a diagnostic tool isn’t limited to the underlying disease biology, however. It also can help diagnose and determine targeted therapies for patients with unexplained illnesses. Mrinal Patnaik, M.B.B.S., a Mayo Clinic hematologist, and colleagues […]
Tags: blood cancer, Center for Individualized Medicine, genomics, hematology, Mayo Clinic Proceedings, Mrinal Patnaik, precision medicine
March 28, 2019
When the shoelaces fray: short telomere syndromes
By Advancing the Science contributor
Article by Barbara Toman Unlike gray hair, one of the most significant signs of aging is invisible to the naked eye. Deep inside cells, at the tips of thread-like chromosomes, structures known as telomeres protect chromosomes from deterioration—a bit like the way caps at the ends of shoelaces prevent fraying. Telomeres naturally shorten as people […]
Tags: Center for Individualized Medicine, DNA, genetics, Mrinal Patnaik, short telomere syndrome
August 1, 2018
Mentorship program makes research aspirations a reality
Mrinal Patnaik, M.B.B.S., is a physician in the Department of Hematology at Mayo Clinic with a keen interest in the clinical management of blood cancers. In recent years, however, Dr. Patnaik realized he wanted to develop a deeper understanding of the disease biology of these cancers and the ways that precision genomics could be used […]
Tags: Center for Clinical and Translational Science, Center for Individualized Medicine, education, epigenetics, genomics, hematology, Mrinal Patnaik, research education
January 4, 2018
Gerstner Awardees explore individualized treatments for obesity, rare form of leukemia
By Sharon Rosen Precision medicine research has shown that one size does not fit all when it comes to medical care. Early career investigators can bring new ideas and perspectives to the search for treatments tailored to a patient’s unique needs. These are the goals of Andres Acosta, M.D., Ph.D., and Mrinal Patnaik, M.B.B.S. – […]
Tags: Andres Acosta, blood cancer, Center for Individualized Medicine, Mrinal Patnaik, obesity, weight loss