Items Tagged ‘multiple sclerosis’
January 23, 2020
Mayo Clinic research discovers a molecular switch for repairing central nervous system disorders
A molecular switch has the ability to turn on a substance in animals that repairs neurological damage in disorders such as multiple sclerosis (MS), Mayo Clinic researchers discovered. The early research in animal models could advance an already approved Food and Drug Administration therapy and also could lead to new strategies for treating diseases of the central nervous […]
Tags: Alzheimer's disease, autoimmune disorder, basic science, Center for Regenerative Medicine, demyelination, discovery research, Isobel Scarisbrick, multiple sclerosis, neurology, schizophrenia, spinal cord injury
August 20, 2019
McArdle’s sign, long overlooked, is an indicator of multiple sclerosis
By Advancing the Science contributor 
By Jay Furst McArdle’s sign, a distinctive muscle weakness that affects patients with spinal cord disease, was first noted more than 30 years ago. The namesake of the “sign,” M.J. McArdle, was a professor of neurology in London, and one of his patients with advanced multiple sclerosis needed to extend his neck and tip his […]
Tags: Brian Weinshenker, Ernest Hoffman, Matt Hoffman, Mayo Clinic Proceedings, MS, multiple sclerosis, Nathan Schilaty, neurology, physiology
May 20, 2019
Leading and learning in neurological research
By Advancing the Science contributor
Mayo shares neurological research and advancements at AAN meeting Among more than 15,000 attendees at the 2019 American Academy of Neurology (AAN) Annual Meeting in Philadelphia, May 4-10, Mayo Clinic had a strong presence. Mayo scientists and clinicians led 38 courses and gave 84 lectures at the world’s largest gathering of neurologists. Nearly 60 Mayo […]
Tags: Alejandro Rabinstein, Allen Aksamit, Alyx Porter, Angelman syndrome, autoimmune disorder, brain tumor, Bryan Neth, Christopher Boes, Claudia Lucchinetti, David Dodick, Diego Carvalho, Eugene Scharf
April 11, 2019
Researching the immune system to provide relief from autoimmune encephalitis
By Advancing the Science contributor
Shuronda Hester had just started college and was looking forward to a new chapter in her young life when mysterious and frightening symptoms derailed her plans. Shuronda began having seizures and becoming “increasingly confused, at one point asking for her great-grandmother who passed away eight years ago,” reports First Coast News. Three trips to a hospital […]
Tags: autoimmune disorder, Jason Siegel, MS, multiple sclerosis, neurology
December 27, 2018
Be the life [science] of the party
Looking for a scientific conversation starter for New Year’s Eve? Advancing the Science has you covered with this top-10 recap of our hottest medical research stories from 2018. With this list in your back pocket, you’ll never run out of interesting cocktail banter. And we guarantee you’ll wow your friends with your scientific smarts. #1 […]
Tags: celiac disease, end of life care, fetal surgery, gluten free, Imad Absah, liver disease, Mark Truty, maternal and fetal medicine, multiple sclerosis, nephrology, neuroimmunology, palliative care
November 8, 2018
MS or not MS? Mayo Clinic Neuroimmunology Lab answers the question
By Advancing the Science contributor
In 2017, Mayo Clinic launched a first-in-the-U.S. clinical test to help patients with some autoimmune disorders get the right diagnosis faster. The test defines a new form of inflammatory demyelinating disease, myelin oligodendrocyte glycoprotein (MOG) autoimmunity, which is distinct from multiple sclerosis (MS), with which it is commonly confused. The test uses live cells to […]
Tags: acute flaccid myelitis, Andrew McKeon, biomarkers, Department of Laboratory Medicine and Pathology, MOG antibody, multiple sclerosis, neuroimmunology, neurology, Sean Pittock, transverse myelitis, Vanda Lennon
September 14, 2015
Human antibody can delay Lou Gehrig’s Disease in two mouse models
Researchers at Mayo Clinic and the University of Minnesota have successfully used a single dose of a natural human antibody to delay degeneration of spinal cord neurons in two distinct mouse models of amyotrophic lateral sclerosis (ALS or Lou Gehrig’s disease). The study, published in Disease Models & Mechanisms, suggests new possible therapies for patients […]
Tags: Center for Clinical and Translational Science, multiple sclerosis
March 20, 2015
Hope for reversing multiple sclerosis
By bobnellis 
In 1983, when Moses Rodriguez, M.D., established a small research lab to study multiple sclerosis (MS) at Mayo Clinic, he was told that he was wasting his time. Dr. Rodriguez, now an emeritus staff member, was trained as a physician in neurology. Adding basic science research to his portfolio would be impossible, he was told. […]
Tags: biomedical research, multiple sclerosis, neurosciences