Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘Nagarajan Kannan’

September 22, 2022

A preclinical step toward treating chronic dry mouth

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic researchers replicated chronic dry mouth from radiation damage in preclinical models, laying the foundation for stem cell research to regenerate salivary tissue after cancer. This discovery uses targeted X-radiation to mimic human injury and establish a lab model for testing cellular therapies for dry mouth. The study is published in Radiation Research. “The […]

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Tags: basic science, Center for Regenerative Medicine, discovery research, dry mouth, head and neck cancer, Jeffrey Janus, medical research, Nagarajan Kannan, otolaryngology, quality of life, radiation therapy, salivary glands


October 7, 2020

Mining the molecular origins of breast cancer for new cures

By Susan Buckles Susan Buckles (@susanbuckles)

October is Breast Cancer Awareness Month, a time to focus on new strategies for prevention and early detection. Mayo Clinic Center for Regenerative Medicine and Mayo Clinic Cancer Center support stem cell biology research to uncover the molecular origins of breast cancer in order to bring new cures to the practice. Answering what are the […]

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Tags: BRCA1, BRCA2, Center for Regenerative Medicine, mammary gland research, Nagarajan Kannan


June 11, 2020

Seeking a regenerative therapy for chronic dry mouth

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic researchers are seeking a regenerative therapy for a vexing problem, particularly among cancer patients. How can medical providers treat a condition in which the mouth is so parched that it has an incessant feeling of a cotton lining? Xerostomia, also known as chronic dry mouth, is an agonizing side effect of injury to […]

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Tags: biobank, cancer, Center for Regenerative Medicine, chronic dry mouth, head and neck cancer, Jeffrey Janus, lab medicine, Nagarajan Kannan, salivary glands


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