Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘neurosciences’

January 2, 2019

Toward clinical trials for one type of ALS

By Kate Ledger k8ledger

When a team of Mayo Clinic researchers discovered in 2011 the genetic repeat mutation known as c9orf72, the finding shed new light on amyotrophic lateral sclerosis (ALS). The mutation, which occurs as a short sequence of code repeated hundreds to thousands of times in the gene, is now known to appear in 40 percent of […]

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Tags: ALS, amyotrophic lateral sclerosis, Björn Oskarsson, clinical trials, Dennis Dickson, Kevin Boylan, Leonard Petrucelli, Lou Gehrig's disease, neurology, neurosciences, Rosa Rademakers, Tania Gendron


October 30, 2018

Neuroscience powerhouses at Mayo Clinic in Florida

By Advancing the Science contributor advancingthescience

Rosa Rademakers, Ph.D., and Nilufer Ertekin-Taner, M.D., Ph.D., collaborate on Alzheimer’s disease-related research in the Department of Neuroscience at Mayo Clinic in Florida. Dr. Ertekin-Taner’s lab, which focuses on late-onset Alzheimer’s disease, generates large data sets of gene expression and multilevel genomics data that are shared with Dr. Rademakers’ lab, which focuses, in part, on […]

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Tags: Alzheimer's disease, medical research, neurosciences, Nilufer Ertekin-Taner, Rosa Rademakers


January 9, 2017

Single Allele Mutation Heightens Risk of Early-Onset Parkinson’s

By bobnellis bobnellis

A collaboration of 32 researchers in seven countries, led by scientists at Mayo Clinic’s campus in Florida, found that a mutation in only one allele of a Parkinson’s gene, known as PINK1, increases the risk of early-onset disease. The finding, published recently in the journal Brain, addresses a longstanding debate about whether individuals need to […]

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Tags: gene mutation, neurosciences, Parkinson's disease, Wolfdieter Springer


March 20, 2015

Hope for reversing multiple sclerosis

By bobnellis bobnellis

In 1983, when Moses Rodriguez, M.D., established a small research lab to study multiple sclerosis (MS) at Mayo Clinic, he was told that he was wasting his time. Dr. Rodriguez, now an emeritus staff member, was trained as a physician in neurology. Adding basic science research to his portfolio would be impossible, he was told. […]

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Tags: biomedical research, multiple sclerosis, neurosciences


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