Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘personalized medicine’

September 8, 2021

Genetic variants influence migraine treatment response, according to new Mayo study

By Susan Murphy Susan Murphy (@susanmurphy)

Migraines affect nearly 40 million people in the U.S. Yet pinpointing an effective prophylactic medication ― the most commonly prescribed drugs for people diagnosed with migraines ― remains a long and complex process. Patients often cycle through medications for weeks or months until achieving a therapeutic response.  Now after years of slow progress in migraine therapies […]

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Tags: Center for Individualized Medicine, Fred Cutrer, genetics, migraine, neurology, personalized medicine, pharmacogenomics, Richard Weinshilboum


March 31, 2021

Mayo Clinic researchers explore personalized approach to anti-obesity medications

By Colette Gallagher Colette Gallagher (@colettegallagher)

Individualized medicine initiatives mainly focus on rare diseases or cancer. Little has been attempted to individualize treatment for noncommunicable chronic diseases such as obesity — a chronic, relapsing disease, and a primary cause of Type 2 diabetes, fatty liver disease, cardiovascular disease and cancer. There are many obesity interventions, such as diets, devices, surgery and […]

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Tags: Andres Acosta, Center for Individualized Medicine, genome, genomics, obesity, personalized medicine


March 2, 2021

Mayo Clinic algorithm shows potential in individualizing treatment for depression

By Susan Murphy Susan Murphy (@susanmurphy)

Finding an effective antidepressant medication for people diagnosed with depression, also called major depressive disorder, is often a long and complex process of “try and try again” ― going from one prescription to the next until achieving a therapeutic response. This complex disease, which affects more than 16 million people in the U.S., can cause symptoms of […]

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Tags: Arjun Athreya, artificial intelligence, Center for Individualized Medicine, depression, health technology, individualized medicine, personalized medicine, practice improvement, psychiatry, University of Illinois Urbana-Champaign, William Bobo


December 28, 2020

Mayo study explores benefits of genetic testing for healthy people

By Colette Gallagher Colette Gallagher (@colettegallagher)

More than 1 in 10 people who had predictive genomic testing ― testing that looks for genetic mutations in otherwise healthy people ― learned that they had a hereditary risk for a health condition and may benefit from preventive care, according to a recent study published in Mayo Clinic Proceedings. This study is the first to […]

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Tags: Center for Individualized Medicine, gene mutation, genetic counseling, genetic testing, genomics, hereditary diseases, individualized medicine, Mayo Clinic Proceedings, personalized medicine


February 18, 2020

Mayo researchers studying ‘promising’ new approach to treating advanced cancer, 1 patient at a time, 1 tumor at a time

By Susan Murphy Susan Murphy (@susanmurphy)

A collaborative team of Mayo Clinic scientists is studying an innovative strategy for treating advanced cancer, using genomics and human tumor samples as their guide. The novel approach, called Ex Vivo, creates a miniature cancer replica for testing therapies outside a patient’s body, combined with a comprehensive genomic analysis of a patient’s cancer cells. “We […]

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Tags: biomarkers, cancer, cancer genomics, Center for Individualized Medicine, genomics, George Vasmatzis, individualized medicine, Mayo Clinic Cancer Center, Minetta Liu, Panos Anastasiadis, personalized medicine


September 11, 2019

Targeting therapy to each patient’s unique cancer

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

Article by Sara Damore As DNA sequencing technology helps bring genetic factors driving disease into focus, researchers have developed new cancer therapies to target a patient’s unique cancer, especially for those who do not respond to standard therapy. Funda Meric-Bernstam, M.D., a physician-scientist at MD Anderson Cancer Center, will speak on Decision Support  for Precision […]

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Tags: Alan Bryce, cancer, Center for Individualized Medicine, clinical trials, DNA, genomics, hematology, Mayo Clinic Cancer Center, oncology, personalized medicine


August 14, 2019

Can BioBanks Help Close Gaps in Health Outcomes?

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

By Barbara J. Toman By definition, personalized medicine requires diversity. One-size-fits-all doesn’t work for every individual, especially members of groups that are medically underserved. In collaboration with Arizona State University and Mountain Park Health Center (MPHC) in Phoenix, Mayo Clinic’s Center for Individualized Medicine has created a biobank to enhance the diversity of Mayo’s medical research. Sangre Por Salud (Spanish for Blood […]

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Tags: biobank, Center for Individualized Medicine, diversity, health disparities, individualized medicine, personalized medicine, Richard Caselli, Sangre Por Salud


July 1, 2019

Community preparedness for future outbreaks: Lessons from whooping cough

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

Lately the news has contained many stories of illness or death that could have been prevented by vaccination. Although in 2019 the stories have mostly been about measles, in 2016 it was pertussis, or whooping cough, as it was in 2012, and 2004-2005. The Centers for Disease Control estimates 24.1 million cases of whooping cough […]

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Tags: Center for the Science of Health Care Delivery, Chung-Il Wi, epidemiology, Euijung Ryu, immunization, personalized medicine, pertussis, Rochester Epidemiology Project, vaccines, whooping cough, Young Juhn


March 4, 2019

Research News Roundup-February 2019

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

The Mayo Clinic Research News Roundup includes brief summaries and links to research news releases from the past month. It also connects readers to related resources. Read on for more information from Mayo Clinic Research. Mayo Clinic researchers identify gene that may predict pancreatic cancer in people with Type 2 diabetes Mayo Clinic researchers have identified a […]

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Tags: Alzheimer's disease, cancer, diabetes, gut health, integrative medicine, kidney stones, leprosy, Lotte Dyrbye, lymphoma, Mayo Clinic Proceedings, measles virus, microbiome


January 22, 2019

Pharmacogenomics: finding the right drug, dose for cancer therapy

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

By Sharon Rosen Each year, nearly 300,000 patients receive the lifesaving chemotherapy 5-fluorouracil (5-FU) to treat many types of cancer, including colorectal, breast, bowel, skin, pancreatic, and esophageal cancer. While it can be an effective treatment, it doesn’t work for everyone. In fact, up to 30 percent of those who receive the standard dose can […]

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Tags: cancer, Center for Individualized Medicine, individualized medicine, Mayo Clinic Cancer Center, personalized medicine, pharmacogenomics, Robert Diasio


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