Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘precision medicine’

March 21, 2019

Colon cancer: a new era in cancer screening and detection

By Susan Buckles susanbuckles

March is Colorectal Cancer Awareness Month, a time to focus on one of the most common and preventable forms of cancer. Mayo Clinic is applying a new genomic lens to colorectal and other cancers to identify which are the types that run in families. The answer to that could open new treatment options and also […]

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Tags: cancer genomics, Center for Individualized Medicine, colon cancer, hereditary cancer, Lynch syndrome, Niloy "Jewel" Samadder, precision medicine


August 2, 2018

Research News Roundup-July 2018

By Elizabeth Zimmermann elizabethzimmermann

The Mayo Clinic Research News Roundup includes brief summaries and links to research-related news releases from the past month. It also connects readers to associated resources. Read on for more information from Mayo Clinic Research. Anesthesia, surgery linked to subtle decline in memory and thinking in older adults, Mayo study finds In adults over 70, exposure to general […]

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Tags: aging, Alzheimer's disease, basic science, DNA, genomics, Mayo Clinic Proceedings, Mayo Clinic Study of Aging, neurology, ovarian cancer, precision medicine, Research News Roundup


June 25, 2018

Targeted DNA next-generation sequencing aids the molecular assessment of pancreatic neuroendocrine tumors

By Nicole Brudos Ferrara nicoleferrara

Pancreas neuroendocrine tumors (pNETs) are a collection of rare neoplasms distinct from pancreas ductal adenocarcinoma. Although the molecular profile of pNETs is somewhat unclear, advances in molecular tumor genotyping is one area of research that is advancing the understanding of this disease. In a 2017 article published in Oncotarget, Ferga Gleeson, M.D., M.B., B.Ch., a specialist […]

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Tags: basic science, Center for Individualized Medicine, DNA, Ferga Gleeson, gastroenterology, individualized medicine, pancreatic cancer, precision medicine


June 12, 2018

Genetic testing to enhance multiple myeloma treatment

By Susan Buckles susanbuckles

This article originally appeared on the Center for Individualized Medicine blog on March 6, 2018 Article by Barbara Toman Multiple myeloma is the second most common blood cancer, but most people haven’t heard of it until they or someone they know is diagnosed with the disease. March is Myeloma Action Month — a time to […]

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Tags: Center for Individualized Medicine, DNA testing, genetic testing, individualized medicine, Keith Stewart, Mayo Clinic Cancer Center, multiple myeloma, precision medicine


April 23, 2018

Registration opens for Individualizing Medicine 2018 Conference

By Susan Buckles susanbuckles

This post originally appeared on the Individualized Medicine blog on April 3, 2018. By Sharon Rosen Gene editing, artificial intelligence, pharmacogenomics and a new era of genomic testing to identify and hopefully treat inherited cancer are just a few of the emerging areas of precision medicine that have the potential to transform patient care. These […]

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Tags: Center for Individualized Medicine, genomics, individualized medicine, Individualizing Medicine Conference, microbiome, pharmacogenomics, precision medicine, Timothy Curry


April 19, 2018

Direct-to-consumer genetic testing-a rapidly shifting landscape

By Colette Gallagher colettegallagher

Direct-to-consumer genetic or over the counter testing emerged in the early 2000s as a means of allowing consumers to access information about their genetics without the involvement of a physician. While early models were popular with consumers, they were controversial in medical and regulatory circles. In the January 2018 issue of Mayo Clinic Proceedings authors Megan Allyse Ph.D., […]

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Tags: biomedical ethics, Center for Individualized Medicine, Matthew Ferber, Mayo Clinic Proceedings, Megan Allyse, precision medicine, Richard Sharp


April 10, 2018

New international practice guidelines for using tamoxifen to treat breast cancer

By Colette Gallagher colettegallagher

An international group of clinicians and scientists representing the Clinical Pharmacogenetics Implementation Consortium (CPIC) published the first-ever clinical practice guideline for using CYP2D6 genotype to guide tamoxifen therapy in Clinical Pharmacology and Therapeutics. Tamoxifen is a hormonal agent used for the prevention and treatment of premenopausal and postmenopausal breast cancer that is estrogen receptor positive. CYP2D6 […]

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Tags: breast cancer, Center for Individualized Medicine, genetic testing, Matthew Goetz, Mayo Clinic Cancer Center, pharmacogenomics, precision medicine


May 4, 2017

Precision care for heart disease – a practical approach

By Susan Buckles susanbuckles

Article by Sharon Rosen Heart disease can sometimes be a silent killer. Many of us know seemingly healthy people who’ve suddenly or unexpectedly had a heart attack. It can be shocking when people who are at a a healthy weight and exercise regularly die from heart disease that they never knew they had. Many forms […]

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Tags: Center for Individualized Medicine, genetic testing, genetics, genomics, heart disease, Iftikhar Kullo, John Guidicessi, Mayo Clinic Proceedings, Michael Ackerman, precision medicine


April 27, 2017

Developing new tests to find and defeat cancer at its earliest stages

By Susan Buckles susanbuckles

Mammography and other screening tools have made great strides in finding cancer early, when it is most likely to be successfully treated. However, some early-stage cancers are missed by conventional screening and are only detected when symptoms occur. Mayo Clinic and other research institutions are wondering: could a blood test complement current practice to improve […]

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Tags: breast cancer, cancer, Celine Vachon, Center for Individualized Medicine, clinical trials, Fergus Couch, Mayo Clinic Cancer Center, Minetta Liu, precision medicine


November 15, 2016

The Sangre Por Salud Biobank: Bringing Precision Medicine Research to an Underrepresented Latino Community

By Elizabeth Zimmermann elizabethzimmermann

The Sangre Por Salud (Spanish for Blood for Health) Biobank was created to expand precision medicine research to underrepresented Latino patients in order to enhance the diversity of the Mayo Clinic Biobank. The biobank enables researchers to examine biological samples and data collected from Latino patients in order to develop better prevention, diagnostic tools and […]

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Tags: Arizona State University, biobank, Center for Individualized Medicine, collaboration, Eleanna De Filippis, health disparities, personalized medicine, precision medicine, Sangre Por Salud


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