Items Tagged ‘precision medicine’
December 9, 2021
By Advancing the Science contributor 
When John Giudicessi, M.D., Ph.D., was growing up in Des Moines, Iowa, he fueled his incessant curiosity by taking apart unused items in the family’s basement. He caught frogs and turtles in a backyard creek. He loved figuring out how things worked. His parents encouraged him to ask questions. Dr. Giudicessi says the burgeoning scientist […]
Tags: cardiology, Center for Individualized Medicine, Frank Brozovich, John Giudicessi, medical research, Medical Scientist Training Program, Michael Ackerman, molecular pharmacology and experimental therapeutics, precision medicine, Summer Undergraduate Research Fellowship
November 2, 2021
Unlocking new genetic testing treatment pathways to save time, lives and resources
Genomics experts worldwide released a paper highlighting advances in rare disease, cancer, population health and carrier screening at the 10th Annual Individualizing Medicine Conference on Saturday, Oct. 9. “The use cases we explored in the paper, ‘The Economic Analysis of the Value of Genetic Testing’ are only the tip of the iceberg in the realm of precision medicine,” says co-author Konstantinos […]
Tags: genetic testing, Individualizing Medicine Conference, Konstantinos Lazaridis, liver cancer, lung cancer, population health, precision medicine, rare disease
July 14, 2021
New Mayo study validates melanoma test to help some patients avoid surgical biopsy
By Susan Murphy
More than 100,00 people in the U.S. are expected to be diagnosed with melanoma this year — double the number of cases compared to 30 years ago, according to the American Academy of Dermatology Association. “Melanoma accounts for only about 2% of skin cancers, but it causes a majority of skin cancer deaths,” says Alexander Meves, M.D., a Mayo […]
Tags: Alexander Meves, cancer, cancer genomics, Center for Individualized Medicine, melanoma, precision medicine
July 7, 2021
Mayo researchers study genetic basis of high cholesterol in adults
In a new study published in NPJ Genomic Medicine, Mayo Clinic researchers found that genetic testing may help identify patients with high cholesterol, or hypercholesterolemia. It also may have implications for the clinical management of patients diagnosed with high cholesterol due to a genetic disorder, or familial hypercholesterolemia. “In our study, we found more than 50% of the […]
Tags: Center for Individualized Medicine, cholesterol, genetic testing, hypercholesterolemia, Iftikhar Kullo, precision medicine
July 1, 2021
Early cancer detection test studied at Mayo Clinic is introduced nationally
Mayo Clinic today recognized the debut of a groundbreaking multi-cancer early cancer detection (MCED) test called Galleri™ that can detect more than 50 types of cancers[1] through a simple blood draw. The Galleri test is intended to complement U.S. guideline-recommended cancer screenings. Mayo Clinic Oncologist Minetta Liu, M.D. was involved in the development of the new test. […]
Tags: blood test, cancer, Center for Individualized Medicine, precision medicine
June 29, 2021
Gene fusion discovery in ultrarare tumor highlights potential therapeutic target
By Susan Murphy
A scientific investigation led by a team of researchers from Mayo Clinic’s Center for Individualized Medicine reveals that an ultrarare cancer called epithelioid trophoblastic tumor (ETT), which can develop in the uterus after conception, recurrently exhibits an abnormal fusion of two genes. This fusion creates an unusual protein that triggers aggressive cell growth — the […]
Tags: cancer genomics, Center for Individualized Medicine, precision medicine, rare disease, uterine cancer
April 22, 2021
Mayo researchers reveal gene therapy path for treating children with rare, fatal genetic disease
By Susan Murphy
A gene therapy strategy developed by Mayo Clinic researchers could offer a potential treatment for a rare and fatal genetic disease that often sickens babies in their first days of life. The disease, propionic acidemia, occurs in 1 in 100,000 live births in the U.S. There is no cure. “As soon as the babies start […]
Tags: Center for Individualized Medicine, gene therapy, genomics, precision medicine, rare disease
April 5, 2021
Mayo Clinic Research in the news — 4/5/2021
Mayo Clinic research and faculty experts were featured in a variety of news stories including 3D printed surgical models, early treatment for smoldering multiple myeloma, and heart attacks in women. Updated guideline highlights new therapies, considerations in anaplastic thyroid cancer Healio, 4/1/2021 An updated guideline for best practices in managing anaplastic thyroid cancer stresses the […]
Tags: 3D printing, Alfredo Quinones-Hinojosa, Alzheimer's disease, artificial intelligence, blood cancer, chronic kidney disease, Clifford Jack Jr., COVID-19, digital health, Eric Moore, genetic testing, genetics
April 1, 2021
Research News Roundup — Q1 2021
The first quarter of 2021 saw furthered understanding the SARS-CoV-2 virus and related COVID-19 viral infection. In addition, a number of advances occurred including in genetics knowledge, cancer treatments, as well as interinstitutional collaborations, expanding programs and recognition of some of the most exceptional contributions of current and former Mayo Clinic clinician-scientists. Mayo Clinic and ASU […]
Tags: Arizona State University, biomarkers, brain cancer, BRCA2, breast cancer, chemotherapy, COVID-19, David Holmes Jr., diversity, education, Fergus Couch, gene variant
January 4, 2021
Research News Roundup – Q4 2020
The year 2020 was a time during which medical and many other researchers around the world focused much of their attention and effort on a single topic – the SARS-CoV-2 virus and related COVID-19 viral infection. However, other research continued, findings were published, and evidence built for improvements in health outcomes and delivery of health […]
Tags: antibiotic, artificial intelligence, brain, cancer research, cardiology, cardiovascular medicine, Center for Individualized Medicine, Center for the Science of Health Care Delivery, clinical research, clinical trials, collaboration, coronary artery disease