Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘precision medicine’

February 17, 2020

AI system helps individualize treatment people diagnosed with depression

By Advancing the Science contributor Advancing the Science contributor

When searching for an exact diagnosis through a myriad of complex and serious factors spread across millions of data points, it helps to have a powerful magnifying glass — and another expert point of view. Enter Arjun Athreya, Ph.D., an engineer by trade who has a knack for bringing together data science algorithms and computing […]

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Tags: Arjun Athreya, artificial intelligence, collaboration, data science, depression, individualized medicine, pharmacology, precision medicine, team science, University of Illinois Urbana-Champaign, William Bobo


November 6, 2019

Precision genomics may offer clues to unexplained low blood cell counts

By Advancing the Science contributor Advancing the Science contributor

By Jay Furst Precision genomics has opened the door to identifying the drivers for cancer and other diseases. Its value as a diagnostic tool isn’t limited to the underlying disease biology, however. It also can help diagnose and determine targeted therapies for patients with unexplained illnesses. Mrinal Patnaik, M.B.B.S., a Mayo Clinic hematologist, and colleagues […]

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Tags: blood cancer, Center for Individualized Medicine, genomics, hematology, Mayo Clinic Proceedings, Mrinal Patnaik, precision medicine


October 14, 2019

BEAUTY Update: Progress in breast cancer research

By Advancing the Science contributor Advancing the Science contributor

By Barbara J. Toman Chemotherapy is a standard breast cancer treatment, used for aggressive biology breast cancer to shrink tumors in the breast and lymph nodes before surgery, assess response and destroy any undetected cancer cells elsewhere in the patient. But some breast tumors don’t respond well to chemotherapy, putting patients at high risk of […]

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Tags: breast cancer, cancer, Center for Individualized Medicine, chemotherapy, clinical trials, genetics, genomics, individualized medicine, Judy Boughey, Liewei Wang, Matthew Goetz, Mayo Clinic Cancer Center


March 21, 2019

Colon cancer: a new era in cancer screening and detection

By Susan Buckles Susan Buckles

March is Colorectal Cancer Awareness Month, a time to focus on one of the most common and preventable forms of cancer. Mayo Clinic is applying a new genomic lens to colorectal and other cancers to identify which are the types that run in families. The answer to that could open new treatment options and also […]

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Tags: cancer genomics, Center for Individualized Medicine, colon cancer, hereditary cancer, Lynch syndrome, Niloy "Jewel" Samadder, precision medicine


August 2, 2018

Research News Roundup-July 2018

By Elizabeth Zimmermann Elizabeth Zimmermann

The Mayo Clinic Research News Roundup includes brief summaries and links to research-related news releases from the past month. It also connects readers to associated resources. Read on for more information from Mayo Clinic Research. Anesthesia, surgery linked to subtle decline in memory and thinking in older adults, Mayo study finds In adults over 70, exposure to general […]

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Tags: aging, Alzheimer's disease, basic science, DNA, genomics, Mayo Clinic Proceedings, Mayo Clinic Study of Aging, neurology, ovarian cancer, precision medicine, Research News Roundup


June 25, 2018

Targeted DNA next-generation sequencing aids the molecular assessment of pancreatic neuroendocrine tumors

By Nicole Ferrara Nicole Ferrara

Pancreas neuroendocrine tumors (pNETs) are a collection of rare neoplasms distinct from pancreas ductal adenocarcinoma. Although the molecular profile of pNETs is somewhat unclear, advances in molecular tumor genotyping is one area of research that is advancing the understanding of this disease. In a 2017 article published in Oncotarget, Ferga Gleeson, M.D., M.B., B.Ch., a specialist […]

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Tags: basic science, Center for Individualized Medicine, DNA, Ferga Gleeson, gastroenterology, individualized medicine, pancreatic cancer, precision medicine


June 12, 2018

Genetic testing to enhance multiple myeloma treatment

By Susan Buckles Susan Buckles

This article originally appeared on the Center for Individualized Medicine blog on March 6, 2018 Article by Barbara Toman Multiple myeloma is the second most common blood cancer, but most people haven’t heard of it until they or someone they know is diagnosed with the disease. March is Myeloma Action Month — a time to […]

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Tags: Center for Individualized Medicine, DNA testing, genetic testing, individualized medicine, Keith Stewart, Mayo Clinic Cancer Center, multiple myeloma, precision medicine


April 23, 2018

Registration opens for Individualizing Medicine 2018 Conference

By Susan Buckles Susan Buckles

This post originally appeared on the Individualized Medicine blog on April 3, 2018. By Sharon Rosen Gene editing, artificial intelligence, pharmacogenomics and a new era of genomic testing to identify and hopefully treat inherited cancer are just a few of the emerging areas of precision medicine that have the potential to transform patient care. These […]

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Tags: Center for Individualized Medicine, genomics, individualized medicine, Individualizing Medicine Conference, microbiome, pharmacogenomics, precision medicine, Timothy Curry


April 19, 2018

Direct-to-consumer genetic testing-a rapidly shifting landscape

By Colette Gallagher Colette Gallagher

Direct-to-consumer genetic or over the counter testing emerged in the early 2000s as a means of allowing consumers to access information about their genetics without the involvement of a physician. While early models were popular with consumers, they were controversial in medical and regulatory circles. In the January 2018 issue of Mayo Clinic Proceedings authors Megan Allyse Ph.D., […]

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Tags: biomedical ethics, Center for Individualized Medicine, Matthew Ferber, Mayo Clinic Proceedings, Megan Allyse, precision medicine, Richard Sharp


April 10, 2018

New international practice guidelines for using tamoxifen to treat breast cancer

By Colette Gallagher Colette Gallagher

An international group of clinicians and scientists representing the Clinical Pharmacogenetics Implementation Consortium (CPIC) published the first-ever clinical practice guideline for using CYP2D6 genotype to guide tamoxifen therapy in Clinical Pharmacology and Therapeutics. Tamoxifen is a hormonal agent used for the prevention and treatment of premenopausal and postmenopausal breast cancer that is estrogen receptor positive. CYP2D6 […]

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Tags: breast cancer, Center for Individualized Medicine, genetic testing, Matthew Goetz, Mayo Clinic Cancer Center, pharmacogenomics, precision medicine


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