July 7, 2022
Researchers validate threshold for determining effectiveness of antidepressant treatment
By Advancing the Science contributor
By Lynda De Widt Over one-third of people diagnosed with major depressive disorder don’t respond sufficiently to specific antidepressant treatments. As a result, often patients need to try different options until they find one that is effective. There are validated definitions of good treatment effects. But the definition of ineffective treatment has been less clear, […]
Tags: depression, medication management, patient reported outcomes, pharmacology, psychiatry, William Bobo
April 4, 2022
Research News Roundup — March 2022
By Advancing the Science contributor
March news reports are often focused on college basketball, daylight savings time and Mardi Gras. This year, Ukraine and the its people are top of mind for many, providing a sobering counterpoint. Behind the scenes, research has continued at Mayo Clinic, and several findings were released in March that help build the evidence and point […]
Tags: aging, Alzheimer's disease, animal model, artificial intelligence, biomarkers, chemotherapy, collaboration, COVID-19, depression, discovery research, drug discovery, genomics
March 2, 2021
Mayo Clinic algorithm shows potential in individualizing treatment for depression
By Susan Murphy
Finding an effective antidepressant medication for people diagnosed with depression, also called major depressive disorder, is often a long and complex process of “try and try again” ― going from one prescription to the next until achieving a therapeutic response. This complex disease, which affects more than 16 million people in the U.S., can cause symptoms of […]
Tags: Arjun Athreya, artificial intelligence, Center for Individualized Medicine, depression, health technology, individualized medicine, personalized medicine, practice improvement, psychiatry, University of Illinois Urbana-Champaign, William Bobo
June 3, 2020
Regenerative approaches could foster healing from COVID-19
Regenerative Medicine aims not only to repair or restore the function of cells, tissues or organs, but also the whole person. The latter is particularly important amid the COVID-19 pandemic. Regenerative approaches draw on the body’s natural abilities to heal, focus on establishing the healing environments and building new, healthy ways of functioning. These aspects […]
Tags: Center for Regenerative Medicine, COVID-19, Craig Sawchuk, health sciences research, Ian Hargraves, patient experience, psychiatry, psychology, Victor Montori
March 24, 2020
By Susan Murphy
By Sharon Rosen Patients suffering from depression, anxiety and substance use disorders often search for years to find treatment. Studies have shown that during this time gap, patients’ symptoms worsen, increasing their risk for other chronic illnesses, shortened lifespan and poor quality of life. Mayo Clinic statistical geneticist Joanna Biernacka, Ph.D. and her colleagues are working to […]
Tags: anxiety, biobank, Center for Individualized Medicine, depression, genetic testing, genetics, Joanna Biernacka, Mark Frye, psychiatry, substance abuse disorder
July 24, 2019
Taking the guesswork out of finding the right depression therapy: Meet William Bobo, M.D.
By Advancing the Science contributor
By Sharon Rosen Depression can touch every aspect of a person’s life – affecting the way they think, feel and behave. It is also the leading medical condition for those who complete suicide. Getting the right therapy is crucial. But for patients suffering from the disorder, finding an effective treatment often involves trial and error. […]
Tags: Arjun Athreya, artificial intelligence, Center for Individualized Medicine, genomics, Liewei Wang, mental health, psychiatry, Richard Weinshilboum, University of Illinois Urbana-Champaign, William Bobo
March 14, 2019
Opioid abuse by parents puts children at risk
By Advancing the Science contributor
By Jay Furst Children living in homes where a parent is abusing opioids are clearly impacted, in immediate ways and in ways that may change the trajectory of their lives. Those impacts, however – including the effects on the parent-child relationship – rarely have been studied in depth. It’s a surprising gap in research, considering […]
Tags: adverse childhood events, Kathryn Schak, Magdalena Romanowicz, opioids, psychiatry