Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘stem cells’

June 29, 2020

Research grants aim to advance regenerative medicine toward the practice

By Susan Buckles Susan Buckles

Reprogramming human cells to correct blood disorders such as sickle cell disease, activation of a regenerative pathway to treat liver failure and strategies for skeletal regeneration in patients with brittle bone disease are examples of Mayo Clinic research to be funded through new grants from Regenerative Medicine Minnesota.  Regenerative Medicine Minnesota, a statewide bipartisan initiative, […]

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Tags: clinical trials, Dan Dragomir-Daescu, David Deyle, epigenetics, liver disease, Martin Rodriguez-Porcel, measles virus, nanomedicine, Patricia Devaux, radiation therapy, Regenerative Medicine Minnesota, Rory Smoot


May 21, 2020

A discovery step toward cell replacement therapy for diabetes

By Susan Buckles Susan Buckles

In what could be a step toward cell replacement therapy for diabetes, Mayo Clinic researchers have discovered how to manufacture cells capable of generating a hormone that regulates low blood sugar. Quinn Peterson, Ph.D. and his team have developed a new method of mass producing a cell product containing the hormone glucagon that is capable […]

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Tags: Center for Regenerative Medicine, diabetes, hypoglycemia, pluripotent stem cells, Quinn Peterson, stem cells


April 16, 2020

Mayo Clinic research discovers how stem cells repair damage from heart attacks

By Susan Buckles Susan Buckles

Mayo Clinic researchers have uncovered stem cell-activated mechanisms of healing after a heart attack. Stem cells restored cardiac muscle back to its condition before the heart attack, in turn providing a blueprint of how stem cells may work. The study, published in NPJ Regenerative Medicine, finds that human cardiopoietic cells zero in on damaged proteins to reverse […]

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Tags: Andre Terzic, basic science, cardiac regeneration, cardiovascular disease, Center for Regenerative Medicine, discovery research, heart attack, heart failure, Kent Arrell, mesenchymal stem cells, stem cells


April 1, 2020

Research News Roundup–March 2020

By Elizabeth Zimmermann Elizabeth Zimmermann

Even though it’s April Fool’s Day, the stories we share in this monthly column are no joke. Because since last month our world has shifted focus, we’ve divided these releases into two sections – COVID-related, and everything else. “Everything else” is at the end this month, because it is the bigger section, with nearly a […]

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Tags: AFib, Alzheimer's disease, anesthesiology, cardiology, cardiovascular medicine, clinical trials, COVID-19, Department of Laboratory Medicine and Pathology, FDA, Fredric Meyer, heart attack, heart disease


March 2, 2020

Stem cells in space: A new frontier in regenerative medicine training

By Jennifer Schutz Jennifer Schutz

A Mayo Clinic graduate student is looking to the stars as a new way to advance regenerative therapies for cancer. Rawan Al-Kharboosh, a Ph.D. candidate at Mayo Clinic’s Florida campus, is investigating how stromal vascular fraction stem (SVF) cells react in microgravity and if that may be applied to fight the most deadly type of […]

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Tags: brain cancer, Center for Regenerative Medicine, Rawan Al-Kharboosh, regenerative medicine, stem cells


January 28, 2020

A look into the RAD Labs: Vascular and interventional radiology translational research

By Advancing the Science contributor Advancing the Science contributor

By Maria Ly, undergraduate public affairs intern Sanjay Misra, M.D., an interventional radiologist, in 2010 launched a lab focused on improving existing therapies and creating new treatments to help patients with renal disease. Funded by grants from the National Institutes of Health, American Heart Association, and Mayo Clinic, the Vascular and Interventional Radiology Translational Research […]

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Tags: biomedical research, clinical trials, dialysis, kidney disease, medical innovation, nanomedicine, orphan drug, radiology, research, research education, Sanjay Misra, stem cells


January 27, 2020

Neuro regeneration for chemo brain: Mi-Hyeon Jang, Ph.D.

By Jennifer Schutz Jennifer Schutz

Cognitive dysfunction, sometimes called “chemo brain,” stemming from chemotherapy is a major adverse condition affecting approximately 14 million cancer patients and survivors in the United States. Although chemo brain has been widely reported by patients and clinicians, the cause of concentration and memory problems in cancer patients is not well understood. Mayo Clinic researchers are […]

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Tags: cancer, Center for Regenerative Medicine, chemo brain, chemotherapy, Mayo Clinic Cancer Center, Mi-Hyeon Jang, neuroregeneration, regenerative medicine, Regenerative Medicine Minnesota, stem cells


December 3, 2019

Research News Roundup–November 2019

By Elizabeth Zimmermann Elizabeth Zimmermann

The Mayo Clinic Research News Roundup includes brief summaries and links to research news releases from the past month. It also connects readers to related resources. Read on for more information from Mayo Clinic Research. Case report: Stem cells a step toward improving motor, sensory function after spinal cord injury Stem cells derived from a patient’s own […]

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Tags: arthritis, cancer, carbon ion therapy, cardiology, cholesterol, diabetes, heart attack, IBD, inflammatory bowel disease, Mayo Clinic Cancer Center, Mayo Clinic Proceedings, neurology


November 19, 2019

Researching Stem Cells for Kidney Disease: LaTonya Hickson, M.D.

By Jennifer Schutz Jennifer Schutz

Diabetic kidney disease (DKD) is a serious complication of diabetes. Up to 40 percent of people with diabetes eventually develop kidney disease. With no long-term treatment available, many patients will progress to end stage kidney disease requiring either dialysis or a kidney transplant. Research is underway to keep people from progressing to kidney failure, and the […]

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Tags: Center for Regenerative Medicine, diabetes, kidney disease, kidney failure, LaTonya Hickson, nephrology, regenerative medicine, Regenerative Medicine Minnesota, stem cells


November 12, 2019

Gerstner Regenerative Medicine Initiative: Tracking outcomes and supporting clinical trials

By Jennifer Schutz Jennifer Schutz

One of the challenges of integrating regenerative medicine into daily patient care is that it is so new, there is not a lot of available data to consider when determining best practices. A recent grant will help track information on how patient do after clinical trials. The Gerstner Regenerative Medicine Initiative, funded through a grant from […]

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Tags: Center for Regenerative Medicine, Gerstner Regenerative Medicine Initiative, osteoarthritis, regenerative medicine, stem cells


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