Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

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More in-depth discussions about Mayo Clinic Research departments, programs, initiatives, etc.

September 18, 2019

Genomics and computer science intersect to improve patient care

By Advancing the Science contributor advancingthescience

By Sharon Rosen Computational genomics is a field that brings high-performance computing resources to drive precision medicine research toward new discoveries. However, when over 50 Mayo Clinic physicians, researchers and students gathered in June to participate in the Computational Genomics Course, the emphasis was on the needs of the patient. The annual week-long intensive course […]

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Tags: Center for Individualized Medicine, education, epigenetics, genomics, Justin Nguyen, Nidhi Jalan Sakrikar, research education, Timothy Curry, University of Illinois Urbana-Champaign


September 16, 2019

Research breathes new air into donor lungs

By Advancing the Science contributor advancingthescience

By Sara Nick Four hundred: That’s the number of U.S. patients who die each year awaiting a lung transplant, or are removed from the wait list when they become too ill. Now, cutting-edge research underway on Mayo Clinic’s Florida campus aims to save as many of those lives as possible. “We’re hoping to wipe out […]

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Tags: Abba Zubair, Center for Regenerative Medicine, David Erasmus, ex vivo lung perfusion, Jorge Mallea, lung transplant, pulmonology, regenerative medicine, stem cells, Transplant Center


September 13, 2019

REAL WORLD EVIDENCE in health care improvement

By Elizabeth Zimmermann elizabethzimmermann

In late 2012 Optum and Mayo Clinic came together to form OptumLabs, an open, collaborative research and innovation center, dedicated to improving patient care and patient value through data-driven health care research, leading-edge data science and strong partner collaboration.  Since that time, approximately 150 collaborative projects have led to peer-reviewed publication, a critical step towards […]

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Tags: atrial fibrillation, big data, Center for the Science of Health Care Delivery, clinical trials, OptumLabs, research


September 12, 2019

Behind the scenes–Mayo Clinic Research

By Elizabeth Zimmermann elizabethzimmermann

Everything health care has to offer for patients is the result of research and education related to that research. At Mayo Clinic, research drives everything we do, resulting in evidence-based treatments and continuous improvements in the way patients, caregivers and others experience health care. At Mayo Clinic we share information about our programs and projects […]

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Tags: biomedical ethics, CAR-T, cardiology, cellular therapy, clinical trials, dialysis, Ian Lanza, Januario Castro, kidney disease, medical research, metabolism, neurology


September 9, 2019

Mayo Clinic Cancer Center Renews National Cancer Institute Research Funding

By Nicole Brudos Ferrara nicoleferrara

Mayo Clinic Cancer Center has once again successfully renewed its National Cancer Institute (NCI) Cancer Center Support Grant. The grant award provides roughly $28.7 million in funding over five years through 2024, which will mark Mayo Clinic’s 49th year of NCI funding. Mayo Clinic Cancer Center’s NCI designation as a comprehensive cancer center was also […]

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Tags: cancer, Mayo Clinic Cancer Center, National Cancer Institute, research


September 4, 2019

Mayo experts provide insights into how genes affect medication response

By Advancing the Science contributor advancingthescience

By Sharon Rosen Pharmacogenomics – how a person’s genes affect medication response – is touching virtually every area of medical care.  Findings from the Mayo Clinic RIGHT study (Right Drug, Right Dose, Right Time–Using Genomic Data to Individualize Treatment) showed that 99% of participants had at least one genetic variant that may affect their response […]

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Tags: breast cancer, cancer, cancer genomics, Center for Individualized Medicine, Eric Matey, Lauren Cornell, mental health, Michael Shuh, neurology, opioids, pharmacogenomics, pharmacy


August 27, 2019

Community voices guide use of biobank samples in research

By Caitlin Doran caityrosey

Mayo Clinic supports biobanks—large collections of patient biological samples—near each of its three campuses in Arizona, Florida, and Minnesota, with the goal of supporting research to broaden the understanding of health and disease.  Paired with each biobank, Mayo fields a community advisory board (CAB), whose members are recruited from the local community to help guide […]

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Tags: biobank, Center for Individualized Medicine, community engagement, Richard Sharp, Sangre Por Salud, Suzette Bielinski


August 26, 2019

Hospice research aims to understand process of dying, help loved ones with end-of-life care

By Advancing the Science contributor advancingthescience

While death is inevitable, for patients at Mayo Clinic Health System in Mankato’s Hospice Program, the process of dying is becoming more bearable as a result of several research studies aimed at better understanding. Death, ultimately, is inevitable. It happens to everyone. But for patients at Mayo Clinic Health System in Mankato’s Hospice Program, the process […]

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Tags: Greg Kutcher, hospice, Jacek Soroka, Mayo Clinic Health System, palliative care


August 22, 2019

At Mayo Clinic, one Statistics and Data Management Center oversees hundreds of cancer clinical trials

By Advancing the Science contributor advancingthescience

By Lydia Hansen, undergraduate public affairs intern The Mayo Clinic Cancer Center’s Statistics and Data Management Center is one of the largest and most highly rated statistics and data management centers working with cancer research in the world. The group has an overall portfolio of 361 cancer-related clinical trials and information on more than 185,000 […]

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Tags: cancer, clinical trials, health sciences research, Mayo Clinic Cancer Center, National Cancer Institute, Sumithra Mandrekar


August 14, 2019

Can BioBanks Help Close Gaps in Health Outcomes?

By Advancing the Science contributor advancingthescience

By Barbara J. Toman By definition, personalized medicine requires diversity. One-size-fits-all doesn’t work for every individual, especially members of groups that are medically underserved. In collaboration with Arizona State University and Mountain Park Health Center (MPHC) in Phoenix, Mayo Clinic’s Center for Individualized Medicine has created a biobank to enhance the diversity of Mayo’s medical research. Sangre Por Salud (Spanish for Blood […]

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Tags: biobank, Center for Individualized Medicine, diversity, health disparities, individualized medicine, personalized medicine, Richard Caselli, Sangre Por Salud


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